Emerging hemostatic materials for non-compressible hemorrhage control

R Dong, H Zhang, B Guo - National Science Review, 2022 - academic.oup.com
Non-compressible hemorrhage control is a big challenge in both civilian life and the
battlefield, causing a majority of deaths among all traumatic injury mortalities. Unexpected …

Cell membrane-coated nanoparticles: a novel multifunctional biomimetic drug delivery system

H Liu, YY Su, XC Jiang, JQ Gao - Drug Delivery and Translational …, 2023 - Springer
Recently, nanoparticle-based drug delivery systems have been widely used for the
treatment, prevention, and detection of diseases. Improving the targeted delivery ability of …

A review on the synthesis and development of alginate hydrogels for wound therapy

Y Cao, H Cong, B Yu, Y Shen - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Convenient and low-cost dressings can reduce the difficulty of wound treatment. Alginate gel
dressings have the advantages of low cost and safe usage, and they have obvious potential …

[HTML][HTML] Platelet‐inspired nanomedicine in hemostasis thrombosis and thromboinflammation

S Raghunathan, J Rayes, AS Gupta - Journal of Thrombosis and …, 2022 - Elsevier
Platelets are anucleate cell‐fragments derived predominantly from megakaryocytes in the
bone marrow and released in the blood circulation, with a normal count of 150 000–40 000 …

Enhanced proliferation of visualizable mesenchymal stem cell–platelet hybrid cell for versatile intracerebral hemorrhage treatment

G Wu, Z Liu, C Mu, D Song, J Wang, X Meng, Z Li… - ACS …, 2023 - ACS Publications
The intrinsic features and functions of platelets and mesenchymal stem cells (MSCs)
indicate their great potential in the treatment of intracerebral hemorrhage (ICH). However …

Extracellular vesicles as drivers of immunoinflammation in atherothrombosis

R Suades, MF Greco, T Padró, L Badimon - Cells, 2022 - mdpi.com
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality all
over the world. Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released …

Controlled delivery of vancomycin from collagen-tethered peptide vehicles for the treatment of wound infections

J Hwang, H Huang, MO Sullivan… - Molecular …, 2023 - ACS Publications
Despite the great promise of antibiotic therapy in wound infections, antibiotic resistance
stemming from frequent dosing diminishes drug efficacy and contributes to recurrent …

How I use platelet transfusions

SJ Stanworth, A Shah - Blood, The Journal of the American …, 2022 - ashpublications.org
Platelet transfusions are commonly administered for the prevention or treatment of bleeding
in patients with acquired thrombocytopenia across a range of clinical contexts. Recent data …

Hemostasis without clot formation–how platelets guard the vasculature in inflammation, infection, and malignancy

R Kaiser, R Escaig, L Nicolai - Blood, 2023 - Elsevier
Platelets are key vascular effectors in hemostasis, with activation signals leading to fast
recruitment, aggregation, and clot formation. The canonical process of hemostasis is well …

Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models

S Roullet, N Luc, J Rayes, J Solarz… - Blood, The Journal …, 2023 - ashpublications.org
The lack of innovation in von Willebrand disease (VWD) originates from many factors
including the complexity and heterogeneity of the disease but also from a lack of recognition …