Alzheimer's disease (AD) is behaviorally identified by progressive memory impairment and
pathologically characterized by the triad of β-amyloid plaques, neurofibrillary tangles, and …

Female sex is a leading risk factor for developing Alzheimer's disease (AD). Sexual
dimorphism in AD is gaining attention as clinical data show that women are not only more …

Two-thirds of Americans with Alzheimer's disease are women, indicating a profound
variance between the sexes. Variances exist between the sexes in the age and intensity of …

Alzheimer's disease (AD) is a multifactorial age-related neurodegenerative disease that
today has no effective treatment to prevent or slow its progression. Neuroactive steroids …

Alzheimer's disease (AD) is the most common form of dementia, with over 5. 4 million cases
in the US alone (Alzheimer's Association,). Clinically, AD is defined by the presence of …

Background Thymoquinone (TQ), a biologically active ingredient of Nigella sativa, has anti-
inflammatory, anti-oxidative and neuroprotective properties. Therefore, it could be a good …

Despite decades of extensive research efforts, efficacious therapies for Alzheimer's disease
(AD) are lacking. The multi-factorial nature of AD neuropathology and symptomatology has …

Tauopathies are a group of neurodegenerative diseases that involve pathological changes
to the tau protein. Neuroinflammation is a commonly reported feature of tauopathies that has …

Glycogen synthase kinase-3 (GSK-3) is a positron emission tomography (PET) imaging
target with implications in the pathogenesis of Alzheimer's disease (AD). This preliminary …

Post‐mortem investigations indicate that the locus coeruleus (LC) is the initial site of
hyperphosphorylated pretangle tau, a precursor to neurofibrillary tangles (NFTs) found in …