Recent developments in the chemistry of 1H-and 4H-1, 2, 4-triazoles

AA Abbas, KM Dawood - Advances in Heterocyclic Chemistry, 2023 - Elsevier
Abstract 1H-and 4H-1, 2, 4-Triazoles have wide potent biological applications; therefore,
developing new synthetic routes for such interesting scaffolds is of great importance. The …

Co-delivery of Bcl-2 siRNA and doxorubicin through gold nanoparticle-based delivery system for a combined cancer therapy approach

CÜ Tunç, O Aydin - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
Combinational gene and chemo-therapy approach has been investigated for more effective
treatment of cancer. In this report, we demonstrated a multifunctional carrier system based …

Repurposing of Indomethacin and Naproxen as anticancer agents: progress from 2017 to present

AE Kassab, EM Gedawy - RSC advances, 2024 - pubs.rsc.org
Inflammation is strongly linked to cancer and is essential for the growth and development of
tumors. Targeting inflammation and the mediators involved in the inflammatory process …

Design, synthesis, characterization, antioxidant, antiproliferative activity and molecular docking studies of new transition metal complexes of 1, 2, 4-triazole as …

WA Jawad, AA Balakit, MNA Al-Jibouri, Y Sert… - Journal of Molecular …, 2023 - Elsevier
In the present work, we introduce new transition metal complexes. The complexes are
designed to have 3, 4, 5-trimethoxyphenyl and 2‑hydroxy-4-methoxyphenyl groups …

Investigation of Gold Nanoparticle Naproxen-Derived Conjugations in Ovarian Cancer

CU Tunc, G Kursunluoglu, M Akdeniz, AU Kutlu… - ACS Materials …, 2023 - ACS Publications
Ovarian cancer, which is one of the most diagnosed cancer types among women, maintains
its significance as a global health problem. Several drug candidates have been investigated …

Exploring Synthesis and Chemotherapeutic Potential of Thiosemicarbazide Analogs

A Kumar, R Mishra, A Mazumder… - Anti-Cancer Agents …, 2023 - benthamdirect.com
Background: Cancer is a leading cause of death worldwide, accounting for nearly 10 million
deaths in 2020. Researchers are continually finding new and more effective medications to …

[图书][B] Advances in heterocyclic chemistry

EFV Scriven, CA Ramsden - 2019 - books.google.com
Advances in Heterocyclic Chemistry, Volume 128, is the definitive series in the field—one of
great importance to organic chemists, polymer chemists and many biological scientists …

The anticancer activity of Cuscuta campestris Yunck extract: An combined study of in vitro and in vivo experiments

EK Selvi, G Unal - South African Journal of Botany, 2024 - Elsevier
Globally, the mortality rate attributed to cancer is on a concerning upward trajectory. Cancer,
characterized by aberrations in the normal cell cycle, excessive proliferation, and abnormal …

Sulfur Derivatives of 1, 2, 4-Triazole: Recently Developed Compounds, Structure Activity Relationship, and Biological Activity

AM Jasim, TNA Omar… - Iraqi Journal of …, 2024 - bijps.uobaghdad.edu.iq
The term of heterocyclic chemistry focuses only on heterocyclic compounds, which consider
as a percentage of organic chemistry, they equal to greater than sixty-five. These …

Synthesis and investigation of cytotoxic effects of compounds derived from flurbiprofen

E Gökoğlan, D Dere, İ Bedir, K Yelekçi, D Telci… - Journal of Molecular …, 2023 - Elsevier
Abstract New flurbiprofen derivatives containing 1, 2, 4-triazoline-5-thione (4) and thioethers
(5a-r) were synthesized in this study. The structures of synthesized compounds were …