Peripheral nerve injuries induce a pronounced immune reaction within the spinal cord,
largely governed by microglia activation in both the dorsal and ventral horns. The …

Experimental models such as the facial nerve axotomy paradigm in rodents allow the
systematic and detailed study of the response of neurones and their microenvironment to …

Because the neural differentiation capacity of bone marrow stromal cells (BMSCs) is still a
matter of controversial debate, we performed a thorough investigation into the differentiation …

Methods The authors investigated the ability of ESC-derived neural precursor cells to
migrate and differentiate in a host striatum by using a D3-derived ESC clone that was …

Objective The outcome of peripheral nerve repair is often unsatisfactory, and efficient
therapies are not available. We tested the therapeutic potential of functional mimics of the …

The goal of this study was to investigate if a three dimensional matrix, loaded
homogeneously with Schwann cells and the neurotrophic factor LIF (leukemia inhibitory …

Introduction 3. Peripheral nerve axotomy 3.1. The neuron-glia network and the dynamic
functions of brain and spinal cord 3.2. Neuronal responses to peripheral axon injury …

Previously, we showed that autoimmune (central nervous system myelin‐reactive) T cells
exacerbate tissue damage and impair neurological recovery after spinal cord injury …

Purpose Nimodipine and FK506 (Tacrolimus) are drugs that have been reported to
accelerate peripheral nerve regeneration. We therefore tested these substances aiming to …

Animal models of nerve function have been subject to extensive study in order to understand
and investigate methods which may improve axon regeneration and promote functional …