Immunometabolism plays a fundamental role in health and diseases and involves multiple
genes and signals. Aconitate decarboxylase 1 (ACOD1; also known as IRG1) is emerging …

An improved understanding and characterization of glial activation and its relationship with
white matter injury will likely serve as a novel treatment target to curb post injury …

Blast-induced traumatic brain injury represents a leading cause of injury in modern warfare
with injury pathogenesis poorly understood. Preclinical models of blast injury remain poorly …

The development of an advanced blast simulator (ABS) has enabled the reproducible
generation of single-pulse shock waves that simulate free-field blast with high fidelity …

Trauma-induced heterotopic ossification is an intriguing phenomenon involving the
inappropriate ossification of soft tissues within the body such as the muscle and ligaments …

Exposure to blast events can cause severe trauma to vital organs such as the lungs, ears,
and brain. Understanding the mechanisms behind such blast-induced injuries is of great …

With the rapid increase in the number of blast induced traumatic brain injuries and
associated neuropsychological consequences in veterans returning from the operations in …

Previous work in this laboratory used underwater explosive exposures to isolate the effects
of shock-induced principle stress without shear on rat brain aggregate cultures. The current …

Blast induced neurotrauma (BINT) has been designated as the" signature injury" to
warfighters in the recent military conflicts. The occurrence of traumatic brain injury (TBI) in …

Traumatic brain injury (TBI), which is mainly caused by impact, often results in chronic
neurological abnormalities. Since the pathological changes in vivo during primary …