Low back pain (LBP) is a common disease that imposes a huge social and economic
burden on people. Intervertebral disc (IVD) degeneration (IVDD) is often considered to be …

Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …

Bone diseases are usually caused by abnormal metabolism and death of cells in bones,
including osteoblasts, osteoclasts, osteocytes, chondrocytes, and bone marrow …

Low back pain (LBP) represents a frequent and debilitating condition affecting a large part of
the global population and posing a worldwide health and economic burden. The major …

Low back pain (LBP) is a common and important clinical problem. In addition to pain,
patients are also affected by personal, social, and economic burdens. Intervertebral disc …

Introduction: Initiation and progression of intervertebral disk degeneration are linked to
oxidative stress, with reactive oxygen species being a key factor. Therefore, as a potentially …

Intervertebral disc degeneration (IDD) is the main cause of low back pain (LBP), which
significantly impacts global wellbeing and contributes to global productivity declines …

Intervertebral disk (IVD) degeneration (IVDD) is a main factor in lower back pain, and
immunomodulation plays a vital role in disease progression. The IVD is an immune …

Intervertebral disc (IVD) degeneration and accompanying lower back pain impose global
medical and societal challenges, affecting over 600 million people worldwide. The IVD …

An imbalance in oxidative and inflammatory regulation is the main contributor to
intervertebral disc degeneration (IDD). Hydrogen (H2) therapy is a promising antioxidation …