Blautia—a new functional genus with potential probiotic properties?

X Liu, B Mao, J Gu, J Wu, S Cui, G Wang, J Zhao… - Gut …, 2021 - Taylor & Francis
Blautia is a genus of anaerobic bacteria with probiotic characteristics that occur widely in the
feces and intestines of mammals. Based on phenotypic and phylogenetic analyses, some …

[HTML][HTML] Role of gut microbiota in type 2 diabetes pathophysiology

M Gurung, Z Li, H You, R Rodrigues, DB Jump… - …, 2020 - thelancet.com
A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota

K Hosomi, M Saito, J Park, H Murakami… - Nature …, 2022 - nature.com
The gut microbiome is an important determinant in various diseases. Here we perform a
cross-sectional study of Japanese adults and identify the Blautia genus, especially B …

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

M Foretz, B Guigas, B Viollet - Nature Reviews Endocrinology, 2019 - nature.com
Despite its position as the first-line drug for treatment of type 2 diabetes mellitus, the
mechanisms underlying the plasma glucose level-lowering effects of metformin (1, 1 …

Precision microbiome modulation with discrete dietary fiber structures directs short-chain fatty acid production

EC Deehan, C Yang, ME Perez-Muñoz, NK Nguyen… - Cell host & …, 2020 - cell.com
Dietary fibers (DFs) impact the gut microbiome in ways often considered beneficial.
However, it is unknown if precise and predictable manipulations of the gut microbiota, and …

Clostridium species as probiotics: potentials and challenges

P Guo, K Zhang, X Ma, P He - Journal of animal science and …, 2020 - Springer
Clostridium species, as a predominant cluster of commensal bacteria in our gut, exert lots of
salutary effects on our intestinal homeostasis. Up to now, Clostridium species have been …

Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial

Y Wan, F Wang, J Yuan, J Li, D Jiang, J Zhang, H Li… - Gut, 2019 - gut.bmj.com
Objective to investigate whether diets differing in fat content alter the gut microbiota and
faecal metabolomic profiles, and to determine their relationship with cardiometabolic risk …

Impact of gut microbiota and microbiota-related metabolites on hyperlipidemia

X Jia, W Xu, L Zhang, X Li, R Wang… - Frontiers in Cellular and …, 2021 - frontiersin.org
Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been
considered as a high-risk factor and key indicator of many metabolic diseases. The gut …

Depletion of Blautia Species in the Microbiota of Obese Children Relates to Intestinal Inflammation and Metabolic Phenotype Worsening

A Benítez-Páez, EM Gómez del Pugar, I López-Almela… - Msystems, 2020 - Am Soc Microbiol
Cross-sectional studies conducted with obese and control subjects have suggested
associations between gut microbiota alterations and obesity, but the links with specific …

Gut microbiota, a new frontier to understand traditional Chinese medicines

W Feng, H Ao, C Peng, D Yan - Pharmacological Research, 2019 - Elsevier
As an important component of complementary and alternative medicines, traditional
Chinese medicines (TCM) are gaining more and more attentions around the world because …