Wnt–Notch signalling crosstalk in development and disease

GM Collu, A Hidalgo-Sastre, K Brennan - Cellular and molecular life …, 2014 - Springer
Abstract The Notch and Wnt pathways are two of only a handful of highly conserved
signalling pathways that control cell-fate decisions during animal development (Pires …

Understanding the principles of pattern formation driven by notch signaling by integrating experiments and theoretical models

F Bocci, JN Onuchic, MK Jolly - Frontiers in Physiology, 2020 - frontiersin.org
Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides
regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the …

Frizzled2 receives WntA signaling during butterfly wing pattern formation

JJ Hanly, LS Loh, A Mazo-Vargas… - …, 2023 - journals.biologists.com
Butterfly color patterns provide visible and biodiverse phenotypic readouts of the patterning
processes. Although the secreted ligand WntA has been shown to instruct the color pattern …

A Wingless and Notch double‐repression mechanism regulates G1–S transition in the Drosophila wing

H Herranz, L Perez, FA Martín, M Milan - The EMBO journal, 2008 - embopress.org
The control of tissue growth and patterning is orchestrated in various multicellular tissues by
the coordinated activity of the signalling molecules Wnt/Wingless (Wg) and Notch, and …

[HTML][HTML] Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic …

HY Yen, MC Ting, RE Maxson - Developmental biology, 2010 - Elsevier
The Notch pathway is crucial for a wide variety of developmental processes including the
formation of tissue boundaries. That it may function in calvarial suture development and …

Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia

A Nematbakhsh, W Sun, PA Brodskiy… - PLoS computational …, 2017 - journals.plos.org
Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an
abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells …

From Notch signaling to fine-grained patterning: Modeling meets experiments

O Shaya, D Sprinzak - Current opinion in genetics & development, 2011 - Elsevier
Notch signaling is the canonical signaling pathway between neighboring cells. It plays an
important role in fine-grained patterning processes such as the formation of checkerboard …

[HTML][HTML] Mechanics and self-organization in tissue development

P Gómez-Gálvez, S Anbari, LM Escudero… - Seminars in Cell & …, 2021 - Elsevier
Self-organization is an all-important feature of living systems that provides the means to
achieve specialization and functionality at distinct spatio-temporal scales. Herein, we review …

Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing

I Becam, N Rafel, X Hong, SM Cohen… - Development, 2011 - journals.biologists.com
Subdivision of proliferating tissues into adjacent compartments that do not mix plays a key
role in animal development. The Actin cytoskeleton has recently been shown to mediate cell …

Competition in notch signaling with cis enriches cell fate decisions

P Formosa-Jordan, M Ibañes - PloS one, 2014 - journals.plos.org
Notch signaling is involved in cell fate choices during the embryonic development of
Metazoa. Commonly, Notch signaling arises from the binding of the Notch receptor to its …