The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

Psychiatric disorders, including major depressive disorder (MDD), bipolar disorder (BD) and
schizophrenia, affect a significant percentage of the world population. These disorders are …

Associations between influenza infection and psychosis have been reported since the
eighteenth century, with acute “psychoses of influenza” documented during multiple …

The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or …

Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

During pregnancy, programming of the fetal central nervous system establishes
vulnerabilities for emergence of neuropsychiatric phenotypes later in life. Psychosocial …

Evidence shows that gut microbiota may play important roles in schizophrenia pathogenesis
via the “gut-brain” axis, but the mechanisms remain unclear. Here, eighty-four patients with …

Early disruptions to neurodevelopment are highly relevant to understanding both psychiatric
risk and underlying pathophysiology that can be targeted by new treatments. Much …

Schizophrenia is a debilitating disorder that typically begins in adolescence and is
characterized by perceptual abnormalities, delusions, cognitive and behavioural …