Humans exhibit considerable variability in their immune responses to the same immune
challenges. Such variation is widespread and affects individual and population‐level …

Ulcerative colitis (UC) has become a worldwide public health problem, and the prevalence
of the disease among children has been increasing. The pathogenesis of UC has not been …

Patients with Crohn's disease (CD) face malnutrition risk, which, combined with
inflammation, can lead to sarcopenia, associated with a worse prognosis. The purpose of …

Background Genome-wide association studies (GWASs) have identified many single-
nucleotide polymorphisms (SNPs) associated with complex phenotypes in the European …

Inflammatory bowel disease (IBD), a general term encompassing Crohn's disease (CD) and
ulcerative colitis (UC), and other conditions, is a chronic and relapsing autoimmune disease …

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract that results from dysfunction in innate and/or adaptive immune responses. Impaired …

Population genetics continues to identify genetic variants associated with diseases of the
immune system and offers a unique opportunity to discover mechanisms of immune …

IBD, including ulcerative colitis and Crohn's disease, is a chronic and debilitating
gastrointestinal disorder that affects millions of people worldwide. Research on IBD has …

Intestinal epithelial cell (IEC) regulation of barrier function and mucosal homeostasis
enables the establishment of a harmonious gut microenvironment. However, host-derived …

Abstract Background and Aims Microscopic colitis [MC] is currently regarded as an
inflammatory bowel disease that manifests as two subtypes: collagenous colitis [CC] and …