Bat biology, genomes, and the Bat1K project: to generate chromosome-level genomes for all living bat species
Bats are unique among mammals, possessing some of the rarest mammalian adaptations,
including true self-powered flight, laryngeal echolocation, exceptional longevity, unique …
including true self-powered flight, laryngeal echolocation, exceptional longevity, unique …
Limb development: a paradigm of gene regulation
The limb is a commonly used model system for developmental biology. Given the need for
precise control of complex signalling pathways to achieve proper patterning, the limb is also …
precise control of complex signalling pathways to achieve proper patterning, the limb is also …
Six reference-quality genomes reveal evolution of bat adaptations
Bats possess extraordinary adaptations, including flight, echolocation, extreme longevity
and unique immunity. High-quality genomes are crucial for understanding the molecular …
and unique immunity. High-quality genomes are crucial for understanding the molecular …
[HTML][HTML] Progressive loss of function in a limb enhancer during snake evolution
The evolution of body shape is thought to be tightly coupled to changes in regulatory
sequences, but specific molecular events associated with major morphological transitions in …
sequences, but specific molecular events associated with major morphological transitions in …
Recurrent evolution of vertebrate transcription factors by transposase capture
RL Cosby, J Judd, R Zhang, A Zhong, N Garry… - Science, 2021 - science.org
INTRODUCTION How novel protein architectures evolve remains poorly understood. The
rearrangement of domains with preexisting functions into new composite architectures …
rearrangement of domains with preexisting functions into new composite architectures …
Boundary stacking interactions enable cross-TAD enhancer–promoter communication during limb development
TC Hung, DM Kingsley, AN Boettiger - Nature Genetics, 2024 - nature.com
Although promoters and their enhancers are frequently contained within a topologically
associating domain (TAD), some developmentally important genes have their promoter and …
associating domain (TAD), some developmentally important genes have their promoter and …
Large‐scale genome sampling reveals unique immunity and metabolic adaptations in bats
DD Moreno Santillán, TM Lama… - Molecular …, 2021 - Wiley Online Library
Abstract Comprising more than 1,400 species, bats possess adaptations unique among
mammals including powered flight, unexpected longevity, and extraordinary immunity. Some …
mammals including powered flight, unexpected longevity, and extraordinary immunity. Some …
Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding
Vampire bats are the only mammals that feed exclusively on blood. To uncover genomic
changes associated with this dietary adaptation, we generated a haplotype-resolved …
changes associated with this dietary adaptation, we generated a haplotype-resolved …
Comparative analyses of bat genomes identify distinct evolution of immunity in Old World fruit bats
Bats have been identified as natural reservoir hosts of several zoonotic viruses, prompting
suggestions that they have unique immunological adaptations. Among bats, Old World fruit …
suggestions that they have unique immunological adaptations. Among bats, Old World fruit …
Ancient convergent losses of Paraoxonase 1 yield potential risks for modern marine mammals
Mammals diversified by colonizing drastically different environments, with each transition
yielding numerous molecular changes, including losses of protein function. Though not …
yielding numerous molecular changes, including losses of protein function. Though not …