Advanced biomaterials for regulating polarization of macrophages in wound healing

J Mao, L Chen, Z Cai, S Qian, Z Liu… - Advanced Functional …, 2022 - Wiley Online Library
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Biodegradable polymers as the pivotal player in the design of tissue engineering scaffolds

F Zhang, MW King - Advanced healthcare materials, 2020 - Wiley Online Library
Biodegradable polymers play a pivotal role in in situ tissue engineering. Utilizing various
technologies, researchers have been able to fabricate 3D tissue engineering scaffolds using …

Lactic acid in macrophage polarization: The significant role in inflammation and cancer

H Zhou, XY Yan, W Yu, X Liang, X Du… - International reviews …, 2022 - Taylor & Francis
Metabolite lactic acid has always been regarded as a metabolic by-product rather than a
bioactive molecule. Recently, this view has changed since it was discovered that lactic acid …

Electrospun fiber‐based immune engineering in regenerative medicine

Y Xu, Q Saiding, X Zhou, J Wang, W Cui… - Smart Medicine, 2024 - Wiley Online Library
Immune engineering, a burgeoning field within regenerative medicine, involves a spectrum
of strategies to optimize the intricate interplay between tissue regenerative biomaterials and …

Inflammation driven metabolic regulation and adaptation in macrophages

S Gupta, PP Sarangi - Clinical Immunology, 2023 - Elsevier
Macrophages are a diverse population of phagocytic immune cells involved in the host
defense mechanisms and regulation of homeostasis. Usually, macrophages maintain …

Electrospun fiber-based strategies for controlling early innate immune cell responses: towards immunomodulatory mesh designs that facilitate robust tissue repair

D Venugopal, S Vishwakarma, I Kaur, S Samavedi - Acta Biomaterialia, 2023 - Elsevier
Electrospun fibrous meshes are widely used for tissue repair due to their ability to guide a
host of cell responses including phenotypic differentiation and tissue maturation. A critical …

MCP-1-Loaded Poly(l-lactide-co-caprolactone) Fibrous Films Modulate Macrophage Polarization toward an Anti-inflammatory Phenotype and Improve Angiogenesis

C Cheng, H Li, J Liu, L Wu, Z Fang… - ACS Biomaterials Science …, 2023 - ACS Publications
Tissue engineering approaches such as the electrospinning technique can fabricate
nanofibrous scaffolds which are widely used for small-diameter vascular grafting. However …

Dual keratinocyte-attachment and anti-inflammatory coatings for soft tissue sealing around transmucosal oral implants

SK Boda, C Aparicio - Biomaterials Science, 2022 - pubs.rsc.org
Unlike the attachment of soft epithelial skin tissue to penetrating solid natural structures like
fingernails and teeth, sealing around percutaneous/permucosal devices such as dental …

Inducing Immunomodulatory Effects on Human Macrophages by Multifunctional NCO-sP(EO-stat-PO)/Gelatin Hydrogel Nanofibers

MB Taskin, T Tylek, C Blum, C Bohm… - ACS biomaterials …, 2021 - ACS Publications
Endowing materials and scaffolds with immunomodulatory properties has evolved into a
very active field of research. However, combining such effects with multifunctionality …

Functional interleukin-4 releasing microparticles impact THP-1 differentiated macrophage phenotype

IN Lee, JZ Stening, FRAJ Rose… - Frontiers in Bioengineering …, 2024 - frontiersin.org
Introduction Macrophage cell therapies offer potential treatment in inflammatory diseases
due to their ability to mobilize and stimulate their environment. However, successful …