Sarcopenia: aging-related loss of muscle mass and function

L Larsson, H Degens, M Li, L Salviati… - Physiological …, 2019 - journals.physiology.org
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission

FA Meunier, G Schiavo, J Molgó - Journal of Physiology-Paris, 2002 - Elsevier
The neuromuscular junction is one of the most accessible mammalian synapses which
offers a useful model to study long-term synaptic modifications occurring throughout life. It is …

Functional repair of motor endplates after botulinum neurotoxin type A poisoning: biphasic switch of synaptic activity between nerve sprouts and their parent terminals

A de Paiva, FA Meunier, J Molgó… - Proceedings of the …, 1999 - National Acad Sciences
Blockade of acetylcholine release by botulinum neurotoxin type A at the neuromuscular
junction induces the formation of an extensive network of nerve-terminal sprouts. By …

The regulation of bidirectional mitochondrial transport is coordinated with axonal outgrowth

RL Morris, PJ Hollenbeck - Journal of cell science, 1993 - journals.biologists.com
Although small molecules such as ATP diffuse freely in the cytosol, many types of cells
nonetheless position their mitochondria in regions of intense ATP consumption. We …

Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons.

RL Morris, PJ Hollenbeck - The Journal of cell biology, 1995 - rupress.org
A large body of evidence indicates that microtubules (MTs) conduct organelle transport in
axons, but recent studies on extruded squid axoplasm have suggested that actin …

Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophila larvae

HL Atwood, CK Govind, CF Wu - Journal of neurobiology, 1993 - Wiley Online Library
The innervation of ventral longitudinal abdominal muscles (muscles 6, 7, 12, and 13) of third‐
instar Drosophila larvae was investigated with Nomarski, confocal, and electron microscopy …

[图书][B] Body and brain: a trophic theory of neural connections

D Purves - 1988 - books.google.com
The major goal of developmental neurobiology is to understand how the nervous system is
put together. A central theme that has emerged from research in this field over the last …

Multicolor “DiOlistic” labeling of the nervous system using lipophilic dye combinations

WB Gan, J Grutzendler, WT Wong, ROL Wong… - Neuron, 2000 - cell.com
We describe a technique for rapid labeling of a large number of cells in the nervous system
with many different colors. By delivering lipophilic dye-coated particles to neuronal …

Nerve sprouting in muscle is induced and guided by processes extended by Schwann cells

YJ Son, WJ Thompson - Neuron, 1995 - cell.com
Partial denervation or paralysis with botulinum toxin, manipulations that induce sprouting of
nerve terminals in muscle, also induced terminal Schwann cells to extend processes. These …

Quantal acetylcholine release at the vertebrate neuromuscular junction.

W Van Der Kloot, J Molgo - Physiological reviews, 1994 - journals.physiology.org
Our sharpest image of how quanta are released and of how their release is modulated
comes from the neuromuscular junction (NMJ). Our object is to show this picture as we now …