Plant noncoding RNAs: hidden players in development and stress responses

Y Yu, Y Zhang, X Chen, Y Chen - Annual review of cell and …, 2019 - annualreviews.org
A large and significant portion of eukaryotic transcriptomes consists of noncoding RNAs
(ncRNAs) that have minimal or no protein-coding capacity but are functional. Diverse …

Alternative ORFs and small ORFs: shedding light on the dark proteome

MW Orr, Y Mao, G Storz, SB Qian - Nucleic acids research, 2020 - academic.oup.com
Traditional annotation of protein-encoding genes relied on assumptions, such as one open
reading frame (ORF) encodes one protein and minimal lengths for translated proteins. With …

ncRNA-encoded peptides or proteins and cancer

J Wang, S Zhu, N Meng, Y He, R Lu, GR Yan - Molecular Therapy, 2019 - cell.com
Non-coding RNAs (ncRNAs) are unique RNA transcripts that have been widely identified in
the eukaryotic genome and have been shown to play key roles in the development of many …

Whole-genome landscape of Medicago truncatula symbiotic genes

Y Pecrix, SE Staton, E Sallet, C Lelandais-Brière… - Nature Plants, 2018 - nature.com
Advances in deciphering the functional architecture of eukaryotic genomes have been
facilitated by recent breakthroughs in sequencing technologies, enabling a more …

The new function of circRNA: translation

Y Shi, X Jia, J Xu - Clinical and Translational Oncology, 2020 - Springer
Circular RNAs (circRNAs) have been considered a special class of non-coding RNAs
without 5′ caps and 3′ tails which are covalently closed RNA molecules generated by …

Translation termination and ribosome recycling in eukaryotes

CUT Hellen - Cold Spring Harbor perspectives in biology, 2018 - cshperspectives.cshlp.org
Termination of mRNA translation occurs when a stop codon enters the A site of the
ribosome, and in eukaryotes is mediated by release factors eRF1 and eRF3, which form a …

Large-scale analyses of human microbiomes reveal thousands of small, novel genes

H Sberro, BJ Fremin, S Zlitni, F Edfors, N Greenfield… - Cell, 2019 - cell.com
Small proteins are traditionally overlooked due to computational and experimental
difficulties in detecting them. To systematically identify small proteins, we carried out a …

A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation

L Niu, F Lou, Y Sun, L Sun, X Cai, Z Liu, H Zhou… - Science …, 2020 - science.org
Many annotated long noncoding RNAs (lncRNAs) harbor predicted short open reading
frames (sORFs), but the coding capacities of these sORFs and the functions of the resulting …

CircRNA and lncRNA-encoded peptide in diseases, an update review

Q Yi, J Feng, W Lan, H Shi, W Sun, W Sun - Molecular Cancer, 2024 - Springer
Abstract Non-coding RNAs (ncRNAs), including circular RNAs (circRNAs) and long non-
coding RNAs (lncRNAs), are unique RNA molecules widely identified in the eukaryotic …

[HTML][HTML] Prediction of human-virus protein-protein interactions through a sequence embedding-based machine learning method

X Yang, S Yang, Q Li, S Wuchty, Z Zhang - Computational and structural …, 2020 - Elsevier
The identification of human-virus protein-protein interactions (PPIs) is an essential and
challenging research topic, potentially providing a mechanistic understanding of viral …