Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Bile acids are increasingly appearing in the spotlight owing to their novel impacts on various
host processes. Similarly, there is growing attention on members of the microbiota that are …

Microbially derived short-chain fatty acids (SCFAs) in the human gut are tightly coupled to
host metabolism, immune regulation and integrity of the intestinal epithelium. However, the …

Diet and the gut microbiota have a profound influence on physiology and health, however,
mechanisms are still emerging. Here we outline several pathways that gut microbiota …

Despite the potential of oral immunotherapy against food allergy, adverse reactions and loss
of desensitization hinder its clinical uptake. Dysbiosis of the gut microbiota is implicated in …

Nutrition profoundly shapes immunity and inflammation across the lifespan of mammals,
from pre-and post-natal periods to later life. Emerging insights into diet-microbiota …

The intestinal barrier is a precisely regulated semi-permeable physiological structure that
absorbs nutrients and protects the internal environment from infiltration of pathological …

Allergic diseases are a set of chronic inflammatory disorders of lung, skin, and nose
epithelium characterized by aberrant IgE and Th2 cytokine-mediated immune responses to …

Type 2 immune responses form a critical defence against enteric worm infections. In recent
years, mouse models have revealed shared and unique functions for group 2 innate …

The immune response is tailored to the environment in which it takes place. Immune cells
sense and adapt to changes in their surroundings, and it is now appreciated that in addition …