Animal models in eye research: focus on corneal pathologies

A Loiseau, G Raîche-Marcoux, C Maranda… - International Journal of …, 2023 - mdpi.com
The eye is a complex sensory organ that enables visual perception of the world. The
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …

Retinal explant culture: a platform to investigate human neuro‐retina

A Murali, CA Ramlogan‐Steel… - Clinical & …, 2019 - Wiley Online Library
The retina is the tissue responsible for light detection, in which retinal neurons convert light
energy into electrical signals to be transported towards the visual cortex. Damage of retinal …

Ocular half-life of intravitreal biologics in humans and other species: meta-analysis and model-based prediction

A Caruso, M Füth, R Alvarez-Sánchez… - Molecular …, 2019 - ACS Publications
Therapeutic antibodies administered intravitreally are the current standard of care to treat
retinal diseases. The ocular half-life (t 1/2) is a key determinant of the duration of target …

The emerging role of topical ocular drugs to target the posterior eye

L Wang, MB Zhou, H Zhang - Ophthalmology and Therapy, 2021 - Springer
The prevalence of chronic fundus diseases is increasing with the aging of the general
population. The treatment of these intraocular diseases relies on invasive drug delivery …

[HTML][HTML] A parameterized digital 3D model of the Rhesus macaque face for investigating the visual processing of social cues

AP Murphy, DA Leopold - Journal of neuroscience methods, 2019 - Elsevier
Background Rhesus macaques are the most popular model species for studying the neural
basis of visual face processing and social interaction using intracranial methods. However …

Growing tiny eyes: How juvenile jumping spiders retain high visual performance in the face of size limitations and developmental constraints

JT Goté, PM Butler, DB Zurek, EK Buschbeck… - Vision Research, 2019 - Elsevier
Adult jumping spiders are known for their extraordinary eyesight and complex, visually
guided behaviors, including elaborate communicatory displays, navigational abilities, and …

Normative data of ocular biometry, optical coherence tomography, and electrophysiology conducted for cynomolgus macaque monkeys

KE Choi, VTQ Anh, C Yun, YJ Kim… - … Vision Science & …, 2021 - tvst.arvojournals.org
Purpose: To present normative data of optical coherence tomography (OCT) parameters,
electrophysiological tests, and optical biometry conducted for cynomolgus monkeys …

Functional organization of midget and parasol ganglion cells in the human retina

A Kling, AR Gogliettino, NP Shah, EG Wu, N Brackbill… - BioRxiv, 2020 - biorxiv.org
The functional organization of diverse retinal ganglion cell (RGC) types, which shapes the
visual signal transmitted to the brain, has been examined in many species. The unique …

[HTML][HTML] Nonhuman Primate Eyes Display Variable Growth and Aging Rates in Alignment With Human Eyes

Y Xue, Y Cao, S Fan, M Xu, Z Yang… - … & visual science, 2023 - jov.arvojournals.org
Purpose: To assess age-related biometric changes of the eye in nonhuman primates
(NHPs), to and decipher the growth and aging rates and their comparability with humans …

Higher-order-aberrations following hyperopia treatment: small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation

YC Liu, J Wen, EPW Teo, GP Williams… - … vision science & …, 2018 - tvst.arvojournals.org
Purpose: To compare the postoperative higher-order-aberrations (HOAs) after hyperopic
small incision lenticule extraction (SMILE), hyperopic laser-assisted in situ keratomileusis …