Asymmetric Intramolecular Amination Catalyzed with Cp* Ir-SPDO via Nitrene Transfer for Synthesis of Spiro-Quaternary Indolinone

SQ Wei, ZH Li, SH Wang, H Chen… - Journal of the …, 2024 - ACS Publications
An asymmetric intramolecular spiro-amination to high steric hindering α-C–H bond of 1, 3-
dicarbonyl via nitrene transfer using inactive aryl azides has been carried out by developing …

Indoloquinoline Alkaloids as Antimalarials: Advances, Challenges, and Opportunities

PT Parvatkar, K Diagne, Y Zhao… - ChemMedChem, 2024 - Wiley Online Library
Malaria infections affect almost half of the world's population, with over 200 million cases
reported annually. Cryptolepis sanguinolenta, a plant native to West Africa, has long been …

A Domino Dearomative ipso-Annulation/Desymmetrization Approach: Stereoselective Access to Tricyclic Alkaloid Skeletons

CR Reddy, AS Prasad, U Ajaykumar - Organic Letters, 2024 - ACS Publications
Herein, we reveal an unprecedented domino annulation of N-benzyl-acrylamides with 1, 3-
dicarbonyls for the assembly of fused tricyclic alkaloid frameworks incorporating a spirocycle …

Electrochemical selenylative ipso-annulation of N-benzylacrylamides to construct seleno-azaspiro [4.5] decadienones

CR Reddy, J Islam, T Nagendraprasad… - Organic & Biomolecular …, 2024 - pubs.rsc.org
Herein, we present the electrochemical synthesis of selenylated azaspiro [4.5]
decadienones through domino selenylation/ipso-annulation of N-benzylacrylamides with …

Chiral synthetic unprecedented spiro [indoline-2, 3'-thiophen]-3-ones via organocatalytic asymmetric sulfa-Michael/aldol cascade reaction

M Zhang, XH Fei, GP Yang, L Cheng, WJ Li… - Organic Chemistry …, 2024 - pubs.rsc.org
An asymmetric sulfa-Michael/aldol cascade reaction of 2-ylideneoxindoles with 1, 4-dithiane-
2, 5-diol catalyzed by squaramide derived from cinchona was first developed to realize the …

Synthesis of C2-spiroindolines based on the cascade reaction of 2-aryl-3H-indoles with cyclopropanols

Y Xueying, X Yuanshuang, Z Xinying… - Chinese Journal of Organic … - sioc-journal.cn
Presented herein is a novel synthesis of C2-spiroindoline derivatives based on the cascade
reaction of 2-aryl-3H-indoles with cyclopropanols. The formation of product involves Rh (III) …