The changing microbial epidemiology in cystic fibrosis

JJ LiPuma - Clinical microbiology reviews, 2010 - Am Soc Microbiol
Infection of the airways remains the primary cause of morbidity and mortality in persons with
cystic fibrosis (CF). This review describes salient features of the epidemiologies of microbial …

Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia

JR Govan, V Deretic - Microbiological reviews, 1996 - Am Soc Microbiol
Respiratory infections with Pseudomonas aeruginosa and Burkholderia cepacia play a
major role in the pathogenesis of cystic fibrosis (CF). This review summarizes the latest …

[HTML][HTML] 2007 guideline for isolation precautions: preventing transmission of infectious agents in health care settings

JD Siegel, E Rhinehart, M Jackson… - American journal of …, 2007 - pmc.ncbi.nlm.nih.gov
Executive Summary The Guideline for Isolation Precautions: Preventing Transmission of
Infectious Agents in Health Care Settings 2007 updates and expands the 1996 Guideline for …

The multifarious, multireplicon Burkholderia cepacia complex

E Mahenthiralingam, TA Urban… - Nature Reviews …, 2005 - nature.com
Abstract The Burkholderia cepacia complex (Bcc) is a collection of genetically distinct but
phenotypically similar bacteria that are divided into at least nine species. Bcc bacteria are …

Clinical significance of microbial infection and adaptation in cystic fibrosis

AR Hauser, M Jain, M Bar-Meir… - Clinical microbiology …, 2011 - Am Soc Microbiol
SUMMARY A select group of microorganisms inhabit the airways of individuals with cystic
fibrosis. Once established within the pulmonary environment in these patients, many of …

Burkholderia cepacia complex bacteria: opportunistic pathogens with important natural biology

E Mahenthiralingam, A Baldwin… - Journal of applied …, 2008 - academic.oup.com
Interaction with plants around their roots and foliage forms the natural habitat for a wide
range of gram‐negative bacteria such as Burkholderia, Pseudomonas and Ralstonia …

Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of …

A Mellmann, J Cloud, T Maier… - Journal of clinical …, 2008 - Am Soc Microbiol
Nonfermenting bacteria are ubiquitous environmental opportunists that cause infections in
humans, especially compromised patients. Due to their limited biochemical reactivity and …

Antibiotic Management of Lung Infections in Cystic Fibrosis. I. The Microbiome, Methicillin-Resistant Staphylococcus aureus, Gram-Negative Bacteria, and Multiple …

JF Chmiel, TR Aksamit, SH Chotirmall… - Annals of the …, 2014 - atsjournals.org
Despite significant advances in treatment strategies targeting the underlying defect in cystic
fibrosis (CF), airway infection remains an important cause of lung disease. In this two-part …

Microbiology of airway disease in patients with cystic fibrosis

PH Gilligan - Clinical microbiology reviews, 1991 - Am Soc Microbiol
Individuals with cystic fibrosis have abbreviated life spans primarily due to chronic airway
infection. A limited number of types of organisms are responsible for these infections, with …

Infection control in cystic fibrosis

L Saiman, J Siegel - Clinical microbiology reviews, 2004 - Am Soc Microbiol
Over the past 20 years there has been a greater interest in infection control in cystic fibrosis
(CF) as patient-to-patient transmission of pathogens has been increasingly demonstrated in …