Introduction: Spirooxindole, a unique and versatile scaffold, has been widely studied in
some fields such as pharmaceutical chemistry and synthetic chemistry. Especially in the …

Pyrazole and its derivatives are considered a privileged N-heterocycle with immense
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …

Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …

This review summarizes the trends in the formation of complex or not so complex
heterocyclic structures through 1, 3-dipolar cycloadditions of azomethine ylides. Diastereo …

Natural goods, medications, and pharmaceutically active substances all contain substituted
oxindoles. Generally, the C-3 stereocenter of the substituents of oxindoles and their absolute …

Indoles are some of the most versatile and common nitrogen-based heterocyclic scaffolds
and are frequently used in the synthesis of various organic compounds. Indole based …

Azomethine ylides are nitrogen-based three-atom components commonly used in [3+ 2]-
cycloaddition reactions with various unsaturated 2π-electron components. These reactions …

In recent years, N-heterocyclic carbenes (NHCs) have established themselves as a
masterful and promising type of organocatalyst for the speedy construction of medicinally …

Abstract Three novel complexes (1, 3 and 4) ligating N-substituted isatin thiosemicarbazone
derivatives have been synthesized and their structural and biological characteristics have …

To combat emerging antimicrobial-resistant microbes, there is an urgent need to develop
new antimicrobials with better therapeutic profiles. For this, a series of 13 new …