Extracellular heme uptake and the challenge of bacterial cell membranes

W Huang, A Wilks - Annual Review of Biochemistry, 2017 - annualreviews.org
Iron is essential for the survival of most bacteria but presents a significant challenge given its
limited bioavailability. Furthermore, the toxicity of iron combined with the need to maintain …

Histamine: a bacterial signal molecule

T Krell, JA Gavira, F Velando, M Fernández… - International Journal of …, 2021 - mdpi.com
Bacteria have evolved sophisticated signaling mechanisms to coordinate interactions with
organisms of other domains, such as plants, animals and human hosts. Several important …

Essential autoproteolysis of bacterial anti-σ factor RsgI for transmembrane signal transduction

C Chen, S Dong, Z Yu, Y Qiao, J Li, X Ding, R Li… - Science …, 2023 - science.org
Autoproteolysis has been discovered to play key roles in various biological processes, but
functional autoproteolysis has been rarely reported for transmembrane signaling in …

Pseudomonas aeruginosa possesses three distinct systems for sensing and using the host molecule haem

JR Otero‐Asman, AI García‐García… - Environmental …, 2019 - Wiley Online Library
Pathogens have developed several strategies to obtain iron during infection, including the
use of iron‐containing molecules from the host. Haem accounts for the vast majority of the …

The role of FoxA, FiuA, and FpvB in iron acquisition via hydroxamate-type siderophores in Pseudomonas aeruginosa

V Will, C Frey, V Normant, L Kuhn, J Chicher, F Volck… - Scientific Reports, 2024 - nature.com
Siderophores are specialized molecules produced by bacteria and fungi to scavenge iron, a
crucial nutrient for growth and metabolism. Catecholate-type siderophores are mainly …

Humic acid enhanced pyrene degradation by Mycobacterium sp. NJS-1

X Li, H Liu, W Yang, H Sheng, F Wang… - Chemosphere, 2022 - Elsevier
The search for nature-based tools to enhance bioremediation is essential for the sustainable
restoration of contaminated ecosystems. Humic acid (HA) is an important component of …

Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction

DCK Chan, I Josts, K Koteva… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane of gram-negative bacteria prevents many antibiotics from reaching
intracellular targets. However, some antimicrobials can take advantage of iron import …

Diversity of extracytoplasmic function sigma (σECF) factor‐dependent signaling in Pseudomonas

JR Otero‐Asman, S Wettstadt, P Bernal… - Molecular …, 2019 - Wiley Online Library
Pseudomonas bacteria are widespread and are found in soil and water, as well as
pathogens of both plants and animals. The ability of Pseudomonas to colonize many …

Up-regulation of ribosomal and carbon metabolism proteins enhanced pyrene biodegradation in fulvic acid-induced biofilm system

M Gu, WW Fang, X Li, W Yang, MG Waigi… - Environmental …, 2022 - Elsevier
The polycyclic aromatic hydrocarbons (PAHs) that enter the aqueous phase usually coexist
with fulvic acid (FA). Therefore, we initiated this investigation to explore the influences of FA …

Bacterial TonB-dependent transducers interact with the anti-σ factor in absence of the inducing signal protecting it from proteolysis

S Wettstadt, FJ Marcos-Torres, JR Otero-Asman… - PLoS …, 2024 - journals.plos.org
Competitive bacteria like the human pathogen Pseudomonas aeruginosa can acquire iron
from different iron carriers, which are usually internalized via outer membrane TonB …