Chromophore based analyses of steady‐state diffuse reflectance spectroscopy: current status and perspectives for clinical adoption

TM Bydlon, R Nachabé, N Ramanujam… - Journal of …, 2015 - Wiley Online Library
Diffuse reflectance spectroscopy is a rapidly growing technology in the biophotonics
community where it has shown promise in its ability to classify different tissues. In the steady …

Tissue biomolecular and microstructure profiles in optical colorectal cancer delineation

MS Nogueira, M Raju, J Gunther… - Journal of Physics D …, 2021 - iopscience.iop.org
Colorectal cancer (CRC) is the 3rd most common and the 2nd most deadly type of cancer
worldwide. Understanding the biochemical and microstructural aspects of carcinogenesis is …

Opportunities and pitfalls in (sub) diffuse reflectance spectroscopy

M Witteveen, DJ Faber, HJCM Sterenborg… - Frontiers in …, 2022 - frontiersin.org
For a long time, steady-state reflectance spectroscopy measurements have been performed
so that diffusion theory could be used to extract tissue optical properties from the reflectance …

Modelling spatially-resolved diffuse reflectance spectra of a multi-layered skin model by artificial neural networks trained with Monte Carlo simulations

SY Tsui, CY Wang, TH Huang, KB Sung - Biomedical optics express, 2018 - opg.optica.org
A robust modelling method was proposed to extract chromophore information in multi-
layered skin tissue with spatially-resolved diffuse reflectance spectroscopy. Artificial neural …

Diffuse reflectance spectroscopy for determination of optical properties and chromophore concentrations of mice internal organs in the range of 350 nm to 1860 nm

MS Nogueira, M Raju, J Gunther… - … Solutions for Better …, 2018 - spiedigitallibrary.org
The development of photomedical modalities for diagnostics and treatment has created a
need for knowledge of the optical properties of the targeted biological tissues. These …

Estimation of optical properties by spatially resolved reflectance spectroscopy in the subdiffusive regime

P Naglič, F Pernuš, B Likar… - Journal of biomedical …, 2016 - spiedigitallibrary.org
We propose and objectively evaluate an inverse Monte Carlo model for estimation of
absorption and reduced scattering coefficients and similarity parameter γ from spatially …

Verification of a two-layer inverse Monte Carlo absorption model using multiple source-detector separation diffuse reflectance spectroscopy

M Sharma, R Hennessy, MK Markey… - Biomedical optics …, 2013 - opg.optica.org
A two-layer Monte Carlo lookup table-based inverse model is validated with two-layered
phantoms across physiologically relevant optical property ranges. Reflectance data for …

Efficient estimation of subdiffusive optical parameters in real time from spatially resolved reflectance by artificial neural networks

M Ivančič, P Naglič, F Pernuš, B Likar, M Bürmen - Optics letters, 2018 - opg.optica.org
Subdiffusive reflectance captured at short source-detector separations provides increased
sensitivity to the scattering phase function and hence allows superficial probing of the tissue …

Machine learning to extract physiological parameters from multispectral diffuse reflectance spectroscopy

MH Nguyen, Y Zhang, F Wang… - Journal of …, 2021 - spiedigitallibrary.org
Significance: Physiological parameters extracted from diffuse reflectance spectroscopy
(DRS) provide clinicians quantitative information about tissue that helps aid in diagnosis …

Importance sampling-accelerated simulation of full-spectrum backscattered diffuse reflectance

J Mao, Y Ling, P Xue, Y Su - Biomedical Optics Express, 2023 - opg.optica.org
The Monte Carlo (MC) method is one of the most widely used numerical tools to model the
light interaction with tissue. However, due to the low photon collection efficiency and the …