Abstract Food and Drug Administration (FDA) has approved a drug product (Spritam®) and
many medical devices manufactured by three-dimensional printing (3DP) processes for …

Abstract Three-dimensional (3D) printing was discovered in the 1980s, and many industries
have embraced it, but the pharmaceutical industry is slow or reluctant to adopt it. Spiritam® …

Opioid abuse is a growing problem and has become a national health crisis over the past
decade in the USA. Oral ingestion, snorting, and injection are the most commonly employed …

Failures surrounding pharmaceutical quality, particularly with respect to product
manufacturing issues and facility remediation, account for the majority of drug shortages and …

Even though the concept of three-dimensional printing (3DP) technology was evolved in
1970s, but its popularity in pharmaceutical field grows manifold during last decade due to …

The design and development of nanoparticle-and microparticle-based delivery systems
incorporating carotenoids into carrier materials offers multiple advantages, including …

Over the past decade, the abuse of prescription opioid drugs has become a national health
crisis in the United States. Pharmaceutical companies, the Food and Drug Administration …

The objective of the present study was to develop extended-release (ER) hot-melt extruded
(HME) abuse-deterrent pellets of acetaminophen, a model drug, by utilizing high molecular …

Solid beverages of effervescent tablets have good taste and portable features and are
favored by consumers, but product quality and nutrition cannot meet the need of increasing …

While polyethylene oxide (PEO)-based matrix tablets are frequently used as abuse-deterrent
dosage forms, there is limited information available regarding how the selection of …