Glyoxalase System in Breast and Ovarian Cancers: Role of MEK/ERK/SMAD1 Pathway
M Alhujaily - Biomolecules, 2024 - mdpi.com
The glyoxalase system, comprising GLO1 and GLO2 enzymes, is integral in detoxifying
methylglyoxal (MGO) generated during glycolysis, with dysregulation implicated in various …
methylglyoxal (MGO) generated during glycolysis, with dysregulation implicated in various …
An Extracellular/Membrane-Bound S100P Pool Regulates Motility and Invasion of Human Extravillous Trophoblast Lines and Primary Cells
Whilst S100P has been shown to be a marker for carcinogenesis, we have shown, in non-
physio-pathological states, that its expression promotes trophoblast motility and invasion but …
physio-pathological states, that its expression promotes trophoblast motility and invasion but …
[HTML][HTML] Ezrin's role in gastric cancer progression: Implications for immune microenvironment modulation and therapeutic potential
Y Zhu, X Zhang, Y Chen, Q Liu, J Yang, X Fan, H Song… - Heliyon, 2024 - cell.com
At present, surgical resection is the most effective method for the treatment of gastric cancer.
However, death caused by inoperable metastasis is still very common, despite research in …
However, death caused by inoperable metastasis is still very common, despite research in …
MISP Is Overexpressed in Intestinal Metaplasia and Gastric Cancer
Gastric cancer is the fifth most common cancer and the fourth cause of global cancer
mortality. The identification of new biomarkers and drug targets is crucial to allow the better …
mortality. The identification of new biomarkers and drug targets is crucial to allow the better …
SIRT7 Inhibits Melanin Synthesis of PIG1 and PIG3V by Suppressing the Succinylation of EZR
Y Ma, H Chang - Clinical, Cosmetic and Investigational …, 2024 - Taylor & Francis
Background Vitiligo is an autoimmune disease characterized by loss of skin pigmentation
and currently has no effective treatment. This study aimed to investigate the function of …
and currently has no effective treatment. This study aimed to investigate the function of …
Myoglobin Inhibits Breast Cancer Cell Fatty Acid Oxidation and Migration via Heme-Dependent Oxidant Production and Not Fatty Acid Binding
AR Johnson, K Rao, BB Zhang, SJ Mullet… - bioRxiv, 2024 - biorxiv.org
The monomeric heme protein myoglobin (Mb), traditionally thought to be expressed
exclusively in cardiac and skeletal muscle, is now known to be expressed in approximately …
exclusively in cardiac and skeletal muscle, is now known to be expressed in approximately …