Background Accurate routine HIV viral load testing is essential for assessing the efficacy of
antiretroviral treatment (ART) regimens and the emergence of drug resistance. While the use …

Background Increased second-line antiretroviral therapy (ART) failure rate narrows future
options for HIV/AIDS treatment. It has critical implications in resource-limited settings; …

Objectives: To measure rates and predictors of virologic failure and switch to second-line
antiretroviral therapy (ART) in South Africa. Design: Observational cohort study. Methods …

This paper presents a protocol using theoretical methods and free software to design and
analyze multivolume digital PCR (MV digital PCR) devices; the theory and software are also …

Background HIV-1 viral load testing is recommended to monitor antiretroviral therapy (ART)
but is not universally available. The aim of our study was to assess monitoring of first-line …

Background An increasing number of people on antiretroviral therapy (ART) in sub-Saharan
Africa has led to declines in HIV related morbidity and mortality. However, virologic failure …

Objective: Routine monitoring of plasma HIV RNA among HIV-infected patients on
antiretroviral therapy (ART) is unavailable in many resource-limited settings. Alternative …

Objectives: To compare outcomes of antiretroviral therapy (ART) in South Africa, where viral
load monitoring is routine, with those in Malawi and Zambia, where monitoring is based on …

Context Long-term antiretroviral therapy (ART) use in resource-limited countries leads to
increasing numbers of patients with HIV taking second-line therapy. Limited access to further …

Background. After the scale-up of antiretroviral therapy (ART) for human immunodeficiency
virus (HIV) infection in Africa, increasing numbers of patients have pretreatment drug …