The exosome journey: from biogenesis to uptake and intracellular signalling

S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …

A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes

S Gurunathan, MH Kang, JH Kim - International journal of …, 2021 - Taylor & Francis
Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …

Exosomes: potential disease biomarkers and new therapeutic targets

MI Mosquera-Heredia, LC Morales, OM Vidal… - Biomedicines, 2021 - mdpi.com
Exosomes are extracellular vesicles released by cells, both constitutively and after cell
activation, and are present in different types of biological fluid. Exosomes are involved in the …

A new infectious unit: extracellular vesicles carrying virus populations

A Kerviel, M Zhang… - Annual Review of Cell and …, 2021 - annualreviews.org
Viral egress and transmission have long been described to take place through single free
virus particles. However, viruses can also shed into the environment and transmit as …

A comprehensive insight into the role of exosomes in viral infection: dual faces bearing different functions

MH Saad, R Badierah, EM Redwan, EM El-Fakharany - Pharmaceutics, 2021 - mdpi.com
Extracellular vesicles (EVs) subtype, exosome is an extracellular nano-vesicle that sheds
from cells' surface and originates as intraluminal vesicles during endocytosis. Firstly, it was …

Extracellular vesicles in viral infections: two sides of the same coin?

ST Martins, LR Alves - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Extracellular vesicles are small membrane structures containing proteins and nucleic acids
that are gaining a lot of attention lately. They are produced by most cells and can be …

Extracellular vesicles in the pathogenesis of viral infections in humans

A Caobi, M Nair, AD Raymond - Viruses, 2020 - mdpi.com
Most cells can release extracellular vesicles (EVs), membrane vesicles containing various
proteins, nucleic acids, enzymes, and signaling molecules. The exchange of EVs between …

Molecular mediators of RNA loading into extracellular vesicles

C Corrado, MM Barreca, C Zichittella, R Alessandro… - Cells, 2021 - mdpi.com
In the last decade, an increasing number of studies have demonstrated that non-coding
RNA (ncRNAs) cooperate in the gene regulatory networks with other biomolecules …

Tetraspanins: host factors in viral infections

CS New, ZY Lee, KS Tan, AHP Wong… - International Journal of …, 2021 - mdpi.com
Tetraspanins are transmembrane glycoproteins that have been shown increasing interest as
host factors in infectious diseases. In particular, they were implicated in the pathogenesis of …

Extracellular vesicles from Zika virus‐infected cells display viral E protein that binds ZIKV‐neutralizing antibodies to prevent infection enhancement

F Zhao, Y Xu, N Liu, D Lv, Y Chen, Z Liu, X Jin… - The EMBO …, 2023 - embopress.org
Mosquito‐borne flaviviruses including Zika virus (ZIKV) represent a public health problem in
some parts of the world. Although ZIKV infection is predominantly asymptomatic or …