Emerging antiviral therapeutics for human adenovirus infection: Recent developments and novel strategies

MJ Dodge, KM MacNeil, TM Tessier, JB Weinberg… - Antiviral research, 2021 - Elsevier
Human adenoviruses (HAdV) are ubiquitous human pathogens that cause a significant
burden of respiratory, ocular, and gastrointestinal illnesses. Although HAdV infections are …

Hallmarks of metabolic reprogramming and their role in viral pathogenesis

CNS Allen, SP Arjona, M Santerre, BE Sawaya - Viruses, 2022 - mdpi.com
Metabolic reprogramming is a hallmark of cancer and has proven to be critical in viral
infections. Metabolic reprogramming provides the cell with energy and biomass for large …

[HTML][HTML] Almost famous: Human adenoviruses (and what they have taught us about cancer)

TM Tessier, MJ Dodge, KM MacNeil, AM Evans… - Tumour Virus …, 2021 - Elsevier
Papillomaviruses, polyomaviruses and adenoviruses are collectively categorized as the
small DNA tumour viruses. Notably, human adenoviruses were the first human viruses …

Metabolic reprogramming in HIV-associated neurocognitive disorders

CNS Allen, SP Arjona, M Santerre… - Frontiers in Cellular …, 2022 - frontiersin.org
A significant number of patients infected with HIV-1 suffer from HIV-associated
neurocognitive disorders (HAND) such as spatial memory impairments and learning …

Phenotypic and functional features of B cells from two different human subcutaneous adipose depots

D Frasca, D Garcia, A Diaz, M Romero, S Thaller… - Plos one, 2023 - journals.plos.org
In this study, we have compared frequencies, phenotype, function and metabolic
requirements of B cells isolated from the breast and abdominal subcutaneous adipose …

Adipocyte commitment of 3T3-L1 cells is required to support human adenovirus 36 productive replication concurrent with altered lipid and glucose metabolism

V Márquez, G Ballesteros, T Dobner… - Frontiers in Cellular and …, 2022 - frontiersin.org
Human adenovirus 36 (HAdV-D36) can cause obesity in animal models, induces an
adipogenic effect and increased adipocyte differentiation in cell culture. HAdV-D36 infection …

Hyper‐metabolic B cells in the spleens of old mice make antibodies with autoimmune specificities

D Frasca, M Romero, D Garcia, A Diaz, BB Blomberg - Immunity & Ageing, 2021 - Springer
Background Aging is associated with increased intrinsic B cell inflammation, decreased
protective antibody responses and increased autoimmune antibody responses. The effects …

A viral interferon regulatory factor degrades RNA-binding protein hnRNP Q1 to enhance aerobic glycolysis via recruiting E3 ubiquitin ligase KLHL3 and decaying …

X Qi, Q Yan, Y Shang, R Zhao, X Ding, SJ Gao… - Cell Death & …, 2022 - nature.com
Reprogramming of host metabolism is a common strategy of viral evasion of host cells, and
is essential for successful viral infection and induction of cancer in the context cancer …

Metabolic Enzymes in Viral Infection and Host Innate Immunity

C Qin, T Xie, WW Yeh, AC Savas, P Feng - Viruses, 2023 - mdpi.com
Metabolic enzymes are central players for cell metabolism and cell proliferation. These
enzymes perform distinct functions in various cellular processes, such as cell metabolism …

Organelle remodeling enhances mitochondrial ATP disruption for blocking neuro-pain signaling in bone tumor therapy

Q Zhang, H Zhuang, X Wen, Y Su, J Wang… - Chemical Engineering …, 2025 - Elsevier
Cancer neuroscience has revealed the pivotal role of neural pathways in tumor progression
and cancer-associated pain, particularly in bone metastases. To address both tumor growth …