Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Biomedical imaging techniques can provide a vast amount of anatomical information,
enabling diagnosis and the monitoring of disease and treatment profile. MRI uniquely offers …

For patients with drug-resistant focal epilepsy, excision of the epileptogenic zone is the most
effective treatment approach. However, the surgery is less effective in the 15–30% of …

Given their potential in a better characterization and diagnosis of major pathologies like
cancer or chronic inflammation, redox-activated Magnetic Resonance Imaging (MRI) probes …

The presence of multiple oxidation and spin states of first-row transition-metal complexes
facilitates the development of switchable MRI probes. Redox-responsive probes capitalize …

The field of molecular and cellular imaging allows molecules and cells to be visualized in
vivo non-invasively. It has uses not only as a research tool but in clinical settings as well, for …

The reduction/oxidation (redox) potential of tissue is tightly regulated in order to maintain
normal physiological processes, but is disrupted in disease states. Thus, the development of …

Abstract Magnetic Resonance Imaging (MRI) is a powerful imaging tool that combined with
the use of contrast agents (CA) provides meaningful and crucial information both in the …

Abstract Injectable Magnetic Resonance Imaging (MRI) contrast agents have been widely
used to provide critical assessments of disease for both clinical and basic science imaging …

An oxidation-responsive contrast agent for magnetic resonance imaging was synthesized
using Eu2+ and liposomes. Positive contrast enhancement was observed with Eu2+, and …