Optical nanopore sensors for quantitative analysis

JP Fried, Y Wu, RD Tilley, JJ Gooding - Nano Letters, 2022 - ACS Publications
Nanopore sensors have received significant interest for the detection of clinically important
biomarkers with single-molecule resolution. These sensors typically operate by detecting …

Challenges in identifying mRNA transcript starts and ends from long-read sequencing data

E Calvo-Roitberg, RF Daniels, AA Pai - Genome Research, 2024 - genome.cshlp.org
Long-read sequencing (LRS) technologies have the potential to revolutionize scientific
discoveries in RNA biology through the comprehensive identification and quantification of …

Localised solid-state nanopore fabrication via controlled breakdown using on-chip electrodes

JP Fried, JL Swett, BP Nadappuram, A Fedosyuk… - Nano Research, 2022 - Springer
Controlled breakdown has recently emerged as a highly accessible technique to fabricate
solid-state nanopores. However, in its most common form, controlled breakdown creates a …

Localized Nanopore Fabrication via Controlled Breakdown

C Ying, T Ma, L Xu, M Rahmani - Nanomaterials, 2022 - mdpi.com
Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and
other biomolecules without the need for fluorescent labeling or chemical modifications. Solid …

High-porosity hybrid bilayer-enabled portable LED plasmonic biosensing

WY Ko, SC Yeh, HW Chu, YC Hsu, KJ Lin - Chemical Communications, 2022 - pubs.rsc.org
A TiO2-nanowire/Au-nanoparticle hybrid layer, possessing nanocavities and a plasmonic
metasurface, can accomplish an entire visible region absorbance, inducing remarkable …

Direct Laser Writing of Zero-Mode Waveguide Nanowells on an Ultrathin Antireflection Substrate

R Wang, Y Yu, H Huang, B Yang - ACS Applied Nano Materials, 2024 - ACS Publications
Zero-mode waveguide (ZMW) nanowells are an important structure for plasmonic
enhancement, which are widely employed in single-molecule sensing. However, the …

Fluorescence methods to probe mass transport and sensing in solid-state nanoporous membranes

S Varol, D Kaya, E Contini, C Gualandi… - Materials …, 2024 - pubs.rsc.org
Single-and multi-nanoporous (1nm–100nm pore size) solid-state membranes (SSNMs)
receive significant attention in various fields, spanning from biosensing to water purification …

Fast Fabrication Nanopores on a PMMA Membrane by a Local High Electric Field Controlled Breakdown

S Fang, D Zeng, S He, Y Li, Z Pang, Y Wang, L Liang… - Sensors, 2024 - mdpi.com
The sensitivity and accuracy of nanopore sensors are severely hindered by the high noise
associated with solid-state nanopores. To mitigate this issue, the deposition of organic …

Fast fabrication of solid-state nanopores for DNA molecule analysis

Y Zhang, D Ma, Z Gu, L Zhan, J Sha - Nanomaterials, 2021 - mdpi.com
Solid-state nanopores have been developed as a prominent tool for single molecule
analysis in versatile applications. Although controlled dielectric breakdown (CDB) is the …

Fabricating Solid-State Nanopores for Single-Molecule Sensing

K Briggs, M Waugh, V Tabard-Cossa - Solid State Nanopores: From …, 2023 - Springer
Solid-state nanopores are a technology poised to disrupt multiple critical fields, including but
not limited to nucleic acid sequencing, proteomics, in vitro diagnostics, drug discovery, and …