[HTML][HTML] Tunneling nanotubes: Reshaping connectivity

C Zurzolo - Current opinion in cell biology, 2021 - Elsevier
Tunneling nanotubes (TNTs), open membranous channels between connected cells,
represent a novel direct way of communication between distant cells for the diffusion of …

Viral and host heterogeneity and their effects on the viral life cycle

JE Jones, V Le Sage, SS Lakdawala - Nature Reviews Microbiology, 2021 - nature.com
Traditionally, the viral replication cycle is envisioned as a single, well-defined loop with four
major steps: attachment and entry into a target cell, replication of the viral genome …

Tunneling nanotubes provide a route for SARS-CoV-2 spreading

A Pepe, S Pietropaoli, M Vos, G Barba-Spaeth… - Science …, 2022 - science.org
Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection represent a major issue in long coronavirus disease. How SARS-CoV-2 …

Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria

R Chakraborty, T Nonaka, M Hasegawa… - Cell Death & …, 2023 - nature.com
Abstract Tunnelling Nanotubes (TNTs) facilitate contact-mediated intercellular
communication over long distances. Material transfer via TNTs can range from ions and …

Peering into tunneling nanotubes—The path forward

D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …

Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids

G Pinto, I Saenz-de-Santa-Maria… - Biochemical …, 2021 - portlandpress.com
Glioblastoma (GBM) is the most aggressive brain cancer and its relapse after surgery,
chemo and radiotherapy appears to be led by GBM stem cells (GSCs). Also, tumor …

Tunneling nanotubes: the fuel of tumor progression?

G Pinto, C Brou, C Zurzolo - Trends in cancer, 2020 - cell.com
Tunneling nanotubes (TNTs) are thin membrane tubes connecting remote cells and allowing
the transfer of cellular content. TNTs have been reported in several cancer in vitro, ex vivo …

Co-infections as modulators of disease outcome: minor players or major players?

P Devi, A Khan, P Chattopadhyay, P Mehta… - Frontiers in …, 2021 - frontiersin.org
Human host and pathogen interaction is dynamic in nature and often modulated by co-
pathogens with a functional role in delineating the physiological outcome of infection. Co …

HIV/Mtb co-infection: from the amplification of disease pathogenesis to an “emerging syndemic”

JM Azevedo-Pereira, D Pires, M Calado, M Mandal… - Microorganisms, 2023 - mdpi.com
Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb) are pathogens
responsible for millions of new infections each year; together, they cause high morbidity and …

Role of tunneling nanotubes in viral infection, neurodegenerative disease, and cancer

V Tiwari, R Koganti, G Russell, A Sharma… - Frontiers in …, 2021 - frontiersin.org
The network of tunneling nanotubes (TNTs) represents the filamentous (F)-actin rich tubular
structure which is connected to the cytoplasm of the adjacent and or distant cells to mediate …