Intravital microscopy is increasingly used to visualize and quantitate dynamic biological
processes at the (sub) cellular level in live animals. By visualizing tissues through imaging …

Angiogenesis is the process through which new blood vessels are formed from preexisting
ones and plays a critical role in several conditions including embryonic development, tissue …

The main challenges for programmed cell death 1 (PD-1)/PD-1 ligand (PD-L1) checkpoint
blockade lie in a lack of sufficient T cell infiltration, tumor immunosuppressive …

Despite increased use of human induced pluripotent stem cell-derived cardiomyocytes
(hiPSC-CMs) for drug development and disease modeling studies, methods to generate …

The generation of functional skeletal muscle tissues from human pluripotent stem cells
(hPSCs) has not been reported. Here, we derive induced myogenic progenitor cells (iMPCs) …

Extracellular microparticles (MPs) can function as drug-delivery vehicles for anticancer
drugs. Here, we show that the softness of MPs derived from tumour-repopulating cells …

Label-free DNA imaging is highly desirable in biology and medicine to perform live imaging
without affecting cell function and to obtain instant histological tissue examination during …

Due to the negative roles of tumor microenvironment (TME) in compromising therapeutic
responses of various cancer therapies, it is expected that modulation of TME may be able to …

Tissue-engineered skeletal muscle can serve as a physiological model of natural muscle
and a potential therapeutic vehicle for rapid repair of severe muscle loss and injury. Here …

High-resolution intravital microscopy through imaging windows has become an
indispensable technique for the long-term visualization of dynamic processes in living …