Recent trends in biocatalysis

D Yi, T Bayer, CPS Badenhorst, S Wu… - Chemical Society …, 2021 - pubs.rsc.org
Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

Photoinduced activation of alkyl chlorides

CL Ji, X Zhai, QY Fang, C Zhu, J Han… - Chemical Society Reviews, 2023 - pubs.rsc.org
In recent years, the activation of unactivated alkyl chlorides through light-induced processes
has emerged as a promising field in radical chemistry, and has led to new transformations in …

Charting the evolution of chemoenzymatic strategies in the syntheses of complex natural products

CN Stout, NM Wasfy, F Chen… - Journal of the American …, 2023 - ACS Publications
Bolstered by recent advances in bioinformatics, genetics, and enzyme engineering, the field
of chemoenzymatic synthesis has enjoyed a rapid increase in popularity and utility. This …

Halogenases: a palette of emerging opportunities for synthetic biology–synthetic chemistry and C–H functionalisation

C Crowe, S Molyneux, SV Sharma, Y Zhang… - Chemical Society …, 2021 - pubs.rsc.org
The enzymatic generation of carbon–halogen bonds is a powerful strategy used by both
nature and synthetic chemists to tune the bioactivity, bioavailability and reactivity of …

Bacterial terpenome

JD Rudolf, TA Alsup, B Xu, Z Li - Natural product reports, 2021 - pubs.rsc.org
Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

Enzymatic cascade reactions in biosynthesis

CT Walsh, BS Moore - Angewandte Chemie International …, 2019 - Wiley Online Library
Enzyme‐mediated cascade reactions are widespread in biosynthesis. To facilitate
comparison with the mechanistic categorizations of cascade reactions by synthetic chemists …

Biological activities of meroterpenoids isolated from different sources

NK Fuloria, RK Raheja, KH Shah, MJ Oza… - Frontiers in …, 2022 - frontiersin.org
Meroterpenoids are natural products synthesized by unicellular organisms such as bacteria
and multicellular organisms such as fungi, plants, and animals, including those of marine …

Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases

JD Rudolf, CY Chang - Natural product reports, 2020 - pubs.rsc.org
Covering: up to July 2019 Terpene synthases (TSs) are responsible for generating much of
the structural diversity found in the superfamily of terpenoid natural products. These elegant …

Recent development of biomimetic halogenation inspired by vanadium dependent haloperoxidase

Z Chen - Coordination Chemistry Reviews, 2022 - Elsevier
Organohalide is one of the most important and useful compounds in organic chemistry,
broadly embodied in diverse bioactive molecules, organic materials and agrochemicals …

Meroterpenoid natural products from Streptomyces bacteria–the evolution of chemoenzymatic syntheses

LAM Murray, SMK McKinnie, BS Moore… - Natural product …, 2020 - pubs.rsc.org
Covering: Up to January 2020 Meroterpenoids derived from the polyketide 1, 3, 6, 8-
tetrahydroxynaphthalene (THN) are complex natural products produced exclusively by …