Synthetic Advantages of Defluorinative C− F Bond Functionalization

LV Hooker, JS Bandar - Angewandte Chemie, 2023 - Wiley Online Library
Much progress has been made in the development of methods to both create compounds
that contain C− F bonds and to functionalize C− F bonds. As such, C− F bonds are becoming …

Enantioselective Hydrogenation toward Chiral 3-Aryloxy Tetrahydrofurans Enabled by Spiro Ir-PNN Catalysts Containing an Unusual 5-Substituted Chiral Oxazoline …

XS Gu, Y Xiong, F Yang, N Yu, PC Yan, JH Xie… - ACS …, 2022 - ACS Publications
An iridium-catalyzed asymmetric hydrogenation of racemic α-aryloxy lactones involving
dynamic kinetic resolution was successfully implemented by chiral spiro PNN-ligands …

Selected Catalytic Reactions

S Monfette, AR Brown, P Dubé, ND Ide… - Practical Synthetic …, 2020 - Wiley Online Library
Significant improvements have been achieved in metal‐mediated processes, often utilizing
catalytic quantities of a transition metal. In pharmaceutical companies, processes ensuing …

Quantitative Determination of AZD3264, a Selective Ikb-Kinase IKK2 Inhibitor, in Dog Plasma by Solvent-Induced Phase Transition Extraction Coupled with HPLC-MS …

G Li, S Liang, K Qiao, C Wang - Journal of AOAC International, 2021 - academic.oup.com
Background AZD3264 is a small molecule inhibitor of selective IkB-kinase IKK2 currently in
preclinical development for the potential treatment of asthma and chronic pulmonary …

NF-κB Role and Potential Drug Targets in Gastrointestinal Cancer

PL Bhukya, R Laxmivandana… - Role of Transcription …, 2017 - Springer
A multifactorial disease cancer arises due to mutation in the gene encoding particular
transcription factor or proteins. Globally cancer is one of the diseases which is responsible …

[PDF][PDF] and Gopinath Meenakshi Sundaram

PL Bhukya, R Laxmivandana - Role of Transcription Factors in …, 2018 - researchgate.net
A multifactorial disease cancer arises due to mutation in the gene encoding particular
transcription factor or proteins. Globally cancer is one of the diseases which are responsible …