Surgical treatment for epilepsy: the potential gap between evidence and practice

N Jetté, JW Sander, MR Keezer - The Lancet Neurology, 2016 - thelancet.com
Findings from randomised controlled trials, along with more than 100 case series and
observational studies, support the efficacy and safety of resective surgery and, more …

Management of epilepsy in older adults: a critical review by the ILAE Task Force on Epilepsy in the elderly

L Piccenna, R O'Dwyer, I Leppik, E Beghi… - …, 2023 - Wiley Online Library
Older adults represent a highly heterogeneous population, with multiple diverse subgroups.
Therefore, an individualized approach to treatment is essential to meet the needs of each …

[图书][B] Epilepsy: a public health imperative

World Health Organization - 2019 - apps.who.int
Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

Epilepsy treatment in adults and adolescents: expert opinion, 2016

JJ Shih, JB Whitlock, N Chimato, E Vargas… - Epilepsy & Behavior, 2017 - Elsevier
Introduction: There are over twenty anti-seizure medications and anti-seizure devices
available commercially in the United States. The multitude of treatment options for seizures …

New‐onset epilepsy in the elderly

LC Vu, L Piccenna, P Kwan… - British journal of clinical …, 2018 - Wiley Online Library
People who are 60 years old and older have the highest incidence of developing new‐onset
epilepsy. The increase of the ageing population has resulted in a greater number of patients …

Adverse event profiles of antiseizure medications and the impact of coadministration on drug tolerability in adults with epilepsy

LM Willems, M van der Goten, F von Podewils, S Knake… - CNS drugs, 2023 - Springer
Background Antiseizure medication (ASM) as monotherapy or in combination is the
treatment of choice for most patients with epilepsy. Therefore, knowledge about the typical …

Epilepsy in an elderly population: classification, etiology and drug resistance

L Hernández-Ronquillo, S Adams, S Ballendine… - Epilepsy research, 2018 - Elsevier
Purpose To characterize epilepsy in an elderly population and describe the prevalence of
drug resistant epilepsy (DRE) using recently validated International League Against …

Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: Implication of oxidative, inflammatory …

MA Nader, H Ateyya, M El-Shafey… - Neurochemistry …, 2018 - Elsevier
The current investigation aimed at studying the anti-epileptogenic effect of sitagliptin. The
possible effect of the drug in combination with pregabalin in pentylenetetrazole (PTZ) …

[HTML][HTML] Outcomes of deviation from treatment guidelines in status epilepticus: a systematic review

P Uppal, M Cardamone, JA Lawson - Seizure, 2018 - Elsevier
Objective Due to a gap between published clinical guidelines on status epilepticus SE and
clinician management of SE, a systematic review was performed to investigate treatment …

Guidelines for dementia or Parkinson's disease with depression or anxiety: a systematic review

Z Goodarzi, B Mele, S Guo, H Hanson, N Jette… - BMC neurology, 2016 - Springer
Background Depression and anxiety remain under-diagnosed and under-treated in those
with neurologic diseases such as dementia or Parkinson's Disease (PD). Our objectives …