Development and Treatments of Inflammatory Cells and Cytokines in Spinal Cord Ischemia‐Reperfusion Injury

P Zhu, J Li, M Fujino, J Zhuang… - Mediators of inflammation, 2013 - Wiley Online Library
During aortic surgery, interruption of spinal cord blood flow might cause spinal cord
ischemia‐reperfusion injury (IRI). The incidence of spinal cord IRI after aortic surgery is up to …

A modern theory of spinal cord ischemia/injury in thoracoabdominal aortic surgery and its implications for prevention of paralysis

MM Wynn, CW Acher - Journal of cardiothoracic and vascular …, 2014 - jcvaonline.com
From the Departments of* Anesthesiology, and† Surgery, University of Wisconsin School of
Medicine and Public Health, Madison WI. Address reprint requests to. Martha M. Wynn, MD …

Anti-apoptotic and neuroprotective effects of Tetramethylpyrazine following spinal cord ischemia in rabbits

LH Fan, KZ Wang, B Cheng, CS Wang, XQ Dang - BMC neuroscience, 2006 - Springer
Background Tetramethylpyrazine (TMP) is one of the most important active ingredients of a
Chinese herb Ligusticum wallichii Franchat, which is widely used in many ischemia …

Hypoxia promotes apoptosis of neuronal cells through hypoxia-inducible factor-1α-microRNA-204-B-cell lymphoma-2 pathway

X Wang, J Li, D Wu, X Bu… - Experimental Biology and …, 2016 - journals.sagepub.com
Neuronal cells are highly sensitive to hypoxia and may be subjected to apoptosis when
exposed to hypoxia. Several apoptosis-related genes and miRNAs involve in hypoxia …

Assessment of disease progression in motor neuron disease

JMC Winhammar, DB Rowe, RD Henderson… - The Lancet …, 2005 - thelancet.com
Motor neuron disease (MND) is characterised by progressive deterioration of the
corticospinal tract, brainstem, and anterior horn cells of the spinal cord. There is no …

Inflammatory mechanisms involved in brain injury following cardiac arrest and cardiopulmonary resuscitation

Y Xiang, H Zhao, J Wang, L Zhang… - Biomedical …, 2016 - spandidos-publications.com
Cardiac arrest (CA) is a leading cause of fatality and long-term disability worldwide. Recent
advances in cardiopulmonary resuscitation (CPR) have improved survival rates; however …

Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits

L Shan, S Ma, X Qiu, Y Zhou, Y Zhang, L Zheng… - BMC neuroscience, 2010 - Springer
Abstract Background Hydroxysafflor Yellow A (HSYA), which is one of the most important
active ingredients of the Chinese herb Carthamus tinctorius L, is widely used in the …

[HTML][HTML] Effects of N-acetylcysteine and pentoxifylline on remote lung injury in a rat model of hind-limb ischemia/reperfusion injury

HA Takhtfooladi, S Hesaraki, F Razmara… - Jornal Brasileiro de …, 2016 - SciELO Brasil
Objective: To investigate the effects of N-acetylcysteine (NAC) and pentoxifylline in a model
of remote organ injury after hind-limb ischemia/reperfusion (I/R) in rats, the lungs being the …

Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial

PN Leigh, M Swash, Y Iwasaki, A Ludolph… - … Lateral Sclerosis and …, 2004 - Taylor & Francis
In November 2002, an advisory board meeting was convened by Novartis Pharma to
provide recommendations and rationale for clinical trials designed to evaluate new …

Pretreatment with Pentoxifylline and N-Acetylcysteine in Liver Ischemia Reperfusion-Induced Renal Injury

B Seifi, M Kadkhodaee, F Delavari, S Mikaeili… - Renal …, 2012 - Taylor & Francis
Background and Aims: Acute hepatic injury causes systematic inflammatory responses
which may finally lead to functional disturbances in remote organs. In this study, the effects …