Immunotherapy remains to be an appealing treatment option for prostate cancer with some
documented promise. Prostate cancer is traditionally considered as an immunologically …

Since the proposition of the pro‐invasive activity of proteolytic enzymes over 70 years ago,
several roles for proteases in cancer progression have been established. About half of the …

Background Inactivating missense mutations in the SPOP gene, encoding speckle‐type
poxvirus and zinc‐finger protein, are one of the most common genetic alterations in prostate …

Background Prostate cancer (PC) is a heterogenous multifocal disease ranging from
indolent to lethal states. For improved treatment-stratification, reliable approaches are …

Glioblastoma (GBM) is the most common malignant brain tumor among adults. Cancer stem
cells (CSCs) are known to drive treatment resistance and recurrence. However, a few CSC …

Quantitative Raman spectroscopy provides information-rich imaging of complex tissues. To
illustrate its ability to characterise early-stage disease, we compared live P4E6, a low-grade …

Abstract Background Prostate cancer (PCa) is a clinically heterogeneous disease. The
creation of an expression‐based subtyping model based on prostate‐specific biological …

Objective To present a recent clinical case of Skene's gland carcinoma and review all
published literature of Skene's gland malignancy with associated treatment and outcomes …

Recent studies identified Midkine (MDK) as playing a key role in immune regulation. In this
study, we aimed to discover the clinical significance and translational relevance in prostate …

Metastatic and high-risk localized prostate cancer respond to hormone therapy but
outcomes vary. Following a pre-specified statistical plan, we used Cox models adjusted for …