Structure and mechanisms of lysine methylation recognition by the chromodomain in gene transcription

KL Yap, MM Zhou - Biochemistry, 2011 - ACS Publications
Histone methylation recognition is accomplished by a number of evolu-tionarily conserved
protein domains, including those belonging to the methylated lysine-binding Royal family of …

Epigenetic markers in the embryonal germ cell development and spermatogenesis

A Odroniec, M Olszewska, M Kurpisz - Basic and Clinical Andrology, 2023 - Springer
Spermatogenesis is the process of generation of male reproductive cells from
spermatogonial stem cells in the seminiferous epithelium of the testis. During …

H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis

A Poleshko, CL Smith, SC Nguyen… - Elife, 2019 - elifesciences.org
Cell-type-specific 3D organization of the genome is unrecognizable during mitosis. It
remains unclear how essential positional information is transmitted through cell division …

Butyrate, an HDAC inhibitor, stimulates interplay between different posttranslational modifications of histone H3 and differently alters G1-specific cell cycle proteins in …

OP Mathew, K Ranganna, FM Yatsu - Biomedicine & Pharmacotherapy, 2010 - Elsevier
HDACs and HATs regulate histone acetylation, an epigenetic modification that controls
chromatin structure and through it, gene expression. Butyrate, a dietary HDAC inhibitor …

Growth factor–induced activation of MSK2 leads to phosphorylation of H3K9me2S10 and corresponding changes in gene expression

KG Wong, YCF Cheng, VH Wu, AA Kiseleva, J Li… - Science …, 2024 - science.org
Extracellular signals are transmitted through kinase cascades to modulate gene expression,
but it remains unclear how epigenetic changes regulate this response. Here, we provide …

Structural role of RKS motifs in chromatin interactions: a molecular dynamics study of HP1 bound to a variably modified histone tail

GV Papamokos, G Tziatzos, DG Papageorgiou… - Biophysical journal, 2012 - cell.com
The current understanding of epigenetic signaling assigns a central role to post-translational
modifications that occur in the histone tails. In this context, it has been proposed that …

Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle

BP Mishra, KI Ansari, SS Mandal - The FEBS journal, 2009 - Wiley Online Library
Mixed lineage leukemias (MLLs) are histone H3 at lysine 4 (H3K4)‐specific methylases that
play a critical role in regulating gene expression in humans. As chromatin condensation …

Phosphorylation of histone H3 at Thr3 is part of a combinatorial pattern that marks and configures mitotic chromatin

Y Markaki, A Christogianni, AS Politou… - Journal of cell …, 2009 - journals.biologists.com
We have previously shown that histone H3 is transiently phosphorylated at Thr3 during
mitosis. Extending these studies, we now report that phosphorylated Thr3 is always in cis to …

Morphogenomics and morphoproteomics: a role for anatomic pathology in personalized medicine

RE Brown - Archives of pathology & laboratory medicine, 2009 - meridian.allenpress.com
Morphogenomics and Morphoproteomics: A Role for Anatomic Pathology in Personalized
Medicine | Archives of Pathology & Laboratory Medicine Skip to Main Content Search …

Aurora1 phosphorylation activity on histone H3 and its cross‐talk with other post‐translational histone modifications in Arabidopsis

D Demidov, S Hesse, A Tewes, T Rutten… - The Plant …, 2009 - Wiley Online Library
The enzymological properties of AtAurora1, a kinase responsible for the cell cycle‐
dependent phosphorylation of histone H3 at S10, and its cross‐talk with other post …