Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …

Adult-born granule cells (abGCs) have been implicated in memory discrimination through a
neural computation known as pattern separation. Here, using in vivo Ca 2+ imaging, we …

Hippocampal subfield CA3 is thought to stably store memories in assemblies of recurrently
connected cells functioning as a collective. However, the collective hippocampal coding …

The hippocampus forms unique neural representations for distinct experiences, supporting
the formation of different memories. 1, 2, 3, 4, 5, 6 Hippocampal representations gradually …

Representational drift refers to the dynamic nature of neural representations in the brain
despite the behavior being seemingly stable. Although drift has been observed in many …

Adult neurogenesis is a unique form of neuronal plasticity in which newly generated
neurons are integrated into the adult dentate gyrus in a process that is modulated by …

The emergent recognition of the gut-brain axis connection has shed light on the role of the
microbiota in modulating the gut-brain axis's functions. Several microbial metabolites, such …

Environmental enrichment (EE) improves memory, particularly the ability to discriminate
similar past experiences. 1, 2, 3, 4, 5, 6 The hippocampus supports this ability via pattern …

空间导航活动时刻在我们的生活中发生, 导航能力在人群中表现出显著的个体差异,
其衰退也是阿尔兹海默症等认知障碍脑疾病的重要早期行为学表现. 以往研究考察了空间导航 …

Neuronal representations of the world are dynamic. A striking example is the rapid
remapping of the hippocampal spatial code, which occurs even when the environment and …