Can probiotics trigger a paradigm shift for cleaning healthcare environments? A narrative review

LA Denkel, A Voss, E Caselli, SJ Dancer… - … Resistance & Infection …, 2024 - Springer
Background The environment of healthcare institutions plays a major role in the
transmission of multidrug resistant organisms (MDRO) and likely in subsequent healthcare …

Molecular epidemiology of carbapenemase-producing Klebsiella pneumoniae in Gauteng South Africa

KT Salvador-Oke, JDD Pitout, G Peirano… - Scientific Reports, 2024 - nature.com
Klebsiella pneumoniae multidrug-resistant (MDR) high-risk clones drive the spread of
antimicrobial resistance (AMR) associated infections, resulting in limited therapeutic options …

Global epidemiology and antimicrobial resistance of Enterobacterales harbouring genes encoding OXA-48-like carbapenemases: insights from the results of the …

YL Lee, WY Wang, WC Ko… - Journal of Antimicrobial …, 2024 - academic.oup.com
Objectives The recent emergence of carbapenem-resistant Enterobacterales poses a major
and escalating threat to global public health. This study aimed to analyse the global …

[HTML][HTML] Emergence of blaNDM-5 and blaOXA-232 Positive Colistin- and Carbapenem-Resistant Klebsiella pneumoniae in a Bulgarian Hospital

R Markovska, P Stankova, G Popivanov, I Gergova… - Antibiotics, 2024 - mdpi.com
The rapid spread of carbapenemase-producing strains has led to increased levels of
resistance among Gram-negative bacteria, especially enterobacteria. The current study …

[HTML][HTML] Molecular, Genetic, and Biochemical Characterization of OXA-484 Carbapenemase, a Difficult-to-Detect R214G Variant of OXA-181

C Gonzalez, S Oueslati, M Rima, R Nermont, L Dortet… - Microorganisms, 2024 - mdpi.com
OXA-244, an R214G variant of OXA-48, is silently spreading worldwide likely because of
difficulties in detection using classical screening media. Here, we characterized two clinical …

First report of a bla NDM-producing extensively drug resistant Klebsiella pneumoniae ST437 in Italy

SC Ranieri, V Fabbrizi, AM D'Amario… - Frontiers in Cellular …, 2024 - frontiersin.org
Carbapenemase-producing Klebsiella pneumoniae strains (CP-Kps) have recently been
observed to spread rapidly worldwide. New Delhi metallo-β-lactamase (NDM) producing …

PathoTracker: an online analytical metagenomic platform for Klebsiella pneumoniae feature identification and outbreak alerting

S Wang, S Sun, Q Wang, H Chen, Y Guo, M Cai… - Communications …, 2024 - nature.com
Abstract Clinical metagenomics (CMg) Nanopore sequencing can facilitate infectious
disease diagnosis. In China, sub-lineages ST11-KL64 and ST11-KL47 Carbapenem …

Clinical and Genomic Characterization of Carbapenem-Resistant Klebsiella pneumoniae with Concurrent Production of NDM and OXA-48-like Carbapenemases in …

S Cerón, Z Salem-Bango, DA Contreras, EL Ranson… - Microorganisms, 2023 - mdpi.com
The global emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) has
become a critical public healthcare concern due to treatment challenges and high mortality …

Diversity and Distribution of β-Lactamase Genes Circulating in Indian Isolates of Multidrug-Resistant Klebsiella pneumoniae

S Shukla, S Desai, A Bagchi, P Singh, M Joshi, C Joshi… - Antibiotics, 2023 - mdpi.com
Klebsiella pneumoniae (Kp) has gained prominence in the last two decades due to its global
spread as a multidrug-resistant (MDR) pathogen. Further, carbapenem-resistant Kp are …

Outer membrane vesicles mediating horizontal transfer of the epidemic blaOXA-232 carbapenemase gene among Enterobacterales

Z Shen, J Qin, G Xiang, T Chen, N Nurxat… - Emerging Microbes & …, 2024 - Taylor & Francis
ABSTRACT OXA-232 is one of the most common OXA-48-like carbapenemase derivatives
and is widely disseminated in nosocomial settings across countries. The bla OXA-232 gene …