N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer

KM Mrozik, OW Blaschuk, CM Cheong… - BMC cancer, 2018 - Springer
In many types of solid tumours, the aberrant expression of the cell adhesion molecule N-
cadherin is a hallmark of epithelial-to-mesenchymal transition, resulting in the acquisition of …

Structural components of synaptic plasticity and memory consolidation

CH Bailey, ER Kandel… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …

Critical period plasticity in local cortical circuits

TK Hensch - Nature Reviews Neuroscience, 2005 - nature.com
Neuronal circuits in the brain are shaped by experience during'critical periods' in early
postnatal life. In the primary visual cortex, this activity-dependent development is triggered …

Sensitive periods in the development of the brain and behavior

EI Knudsen - Journal of cognitive neuroscience, 2004 - direct.mit.edu
Experience exerts a profound influence on the brain and, therefore, on behavior. When the
effect of experience on the brain is particularly strong during a limited period in …

Cadherins in development: cell adhesion, sorting, and tissue morphogenesis

JM Halbleib, WJ Nelson - Genes & development, 2006 - genesdev.cshlp.org
Tissue morphogenesis during development is dependent on activities of the cadherin family
of cell–cell adhesion proteins that includes classical cadherins, protocadherins, and atypical …

Shaping synapses by the neural extracellular matrix

M Ferrer-Ferrer, A Dityatev - Frontiers in neuroanatomy, 2018 - frontiersin.org
Accumulating data support the importance of interactions between pre-and postsynaptic
neuronal elements with astroglial processes and extracellular matrix (ECM) for formation …

Cell adhesion molecules: signalling functions at the synapse

MB Dalva, AC McClelland, MS Kayser - Nature Reviews Neuroscience, 2007 - nature.com
Many cell adhesion molecules are localized at synaptic sites in neuronal axons and
dendrites. These molecules bridge pre-and postsynaptic specializations but do far more …

[HTML][HTML] A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

P Marambaud, J Shioi, G Serban… - The EMBO …, 2002 - embopress.org
E-cadherin controls a wide array of cellular behaviors including cell–cell adhesion,
differentiation and tissue development. Here we show that presenilin-1 (PS1), a protein …

Extracellular matrix molecules and synaptic plasticity

A Dityatev, M Schachner - Nature Reviews Neuroscience, 2003 - nature.com
Interactions between cells and the extracellular matrix (ECM) have long been accepted to
have pivotal roles in neural development and regeneration. Recent data also support the …

Cadherins in brain morphogenesis and wiring

S Hirano, M Takeichi - Physiological reviews, 2012 - journals.physiology.org
Cadherins are Ca2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …