Chemistry enters nucleic acids biology: enzymatic mechanisms of RNA modification

S Boschi-Muller, Y Motorin - Biochemistry (Moscow), 2013 - Springer
Modified nucleotides are universally conserved in all living kingdoms and are present in
almost all types of cellular RNAs, including tRNA, rRNA, sn (sno) RNA, and mRNA and in …

Radical SAM-mediated methylation of ribosomal RNA

V Stojković, DG Fujimori - Methods in enzymology, 2015 - Elsevier
Post-transcriptional modifications of RNA play an important role in a wide range of biological
processes. In ribosomal RNA (rRNA), methylation of nucleotide bases is the predominant …

Trm4 and Nsun2 RNA:m5C Methyltransferases Form Metabolite-Dependent, Covalent Adducts with Previously Methylated RNA

HJ Moon, KL Redman - Biochemistry, 2014 - ACS Publications
Trm4p from Saccharomyces cerevisiae and its mammalian orthologue Nsun2 fabricate 5-
methylcytosine (m5C) in RNA molecules utilizing a dual-cysteine catalytic mechanism …

Identification of the Rate-Determining Step of tRNA-Guanine Transglycosylase from Escherichia coli

GA Garcia, SM Chervin, JD Kittendorf - Biochemistry, 2009 - ACS Publications
The modified RNA base queuine [7-(4, 5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-
deazaguanine] is present in tRNA because of a unique base-exchange process catalyzed …

[PDF][PDF] ХИМИЯ ПРОНИКАЕТ В БИОЛОГИЮ НУКЛЕИНОВЫХ КИСЛОТ: ФЕРМЕНТАТИВНЫЕ МЕХАНИЗМЫ МОДИФИКАЦИИ РНК

С БОШИ-МЮЛЛЕР, Ю МОТОРИН - fbras.ru
По окончании процесса транскрипции, протекающей с участием РНК-полимераз (ы),
большинство первичных РНК транскриптов в клетке проходит дополнительные стадии …

[引用][C] RNA Modifying Enzymes

GA Garcia, JK Hurt, YC Chen - 2010 - Elsevier