Streptococcus pneumoniae causes substantial mortality among children under 5-years-old
worldwide. Polysaccharide conjugate vaccines (PCVs) are highly effective at reducing …

Quorum sensing (QS), an integral component of bacterial communication, is essential in
coordinating the collective response of diverse bacterial pathogens. Central carbon …

Otitis media (OM) is an inflammatory disorder in the middle ear. It is mainly caused by
viruses or bacteria associated with the airways. Streptococcus pneumoniae, Haemophilus …

Biofilm is the primary cause of persistent infections caused by Streptococcus suis (S. suis).
Metabolism and AI-2 quorum sensing are intricately linked to S. suis biofilm formation …

The intestinal lining is protected by a mucous barrier composed predominantly of complex
carbohydrates. Gut microbes employ diverse glycoside hydrolases (GHs) to liberate …

Streptococcus pneumoniae has to cope with the strong oxidant hypochlorous acid (HOCl),
during host–pathogen interactions. Thus, we analyzed the global gene expression profile of …

Competence development in Streptococcus pneumoniae (pneumococcus) is tightly
intertwined with virulence. In addition to genes encoding genetic transformation machinery …

Streptococcus pneumoniae can regulate virulence gene expression by sensing
environmental changes, which is key to its pathogenicity. The global transcription regulator …

Enterococcus faecalis is commonly isolated from single-and mixed-species biofilm-
associated wound infections. As a defense strategy, the host innately restricts iron …