[HTML][HTML] PD-1/PD-L1 pathway: current researches in cancer
Y Han, D Liu, L Li - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
Cancer immunotherapy has been accompanied by promising results over the past few
years. Programmed Cell Death Protein 1 (PD-1) plays a vital role in inhibiting immune …
years. Programmed Cell Death Protein 1 (PD-1) plays a vital role in inhibiting immune …
[HTML][HTML] Contribution of adipose tissue to development of cancer
AJ Cozzo, AM Fuller, L Makowski - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …
[HTML][HTML] Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
Immune checkpoint blockade (ICB) has improved outcomes in some cancers. A major
limitation of ICB is that most patients fail to respond, which is partly attributable to …
limitation of ICB is that most patients fail to respond, which is partly attributable to …
What do we have to know about PD-L1 expression in prostate cancer? A systematic literature review (part 6): correlation of PD-L1 expression with the status of …
A Palicelli, S Croci, A Bisagni, E Zanetti, D De Biase… - Biomedicines, 2022 - mdpi.com
Pembrolizumab (anti-PD-1) is allowed in selected metastatic castration-resistant prostate
cancer (PC) patients showing microsatellite instability/mismatch repair system deficiency …
cancer (PC) patients showing microsatellite instability/mismatch repair system deficiency …
Estrogen Receptor Downregulates Expression of PD-1/PD-L1 and Infiltration of CD8+ T Cells by Inhibiting IL-17 Signaling Transduction in Breast Cancer
C Shuai, X Yang, H Pan, W Han - Frontiers in Oncology, 2020 - frontiersin.org
Background: The relationship between the interleukin 17 (IL-17) family of cytokines and
breast cancer has been widely studied in recent years. Many studies have revealed …
breast cancer has been widely studied in recent years. Many studies have revealed …
Prostate cancer progression: as a matter of fats
N Scaglia, YR Frontini-López, G Zadra - Frontiers in Oncology, 2021 - frontiersin.org
Advanced prostate cancer (PCa) represents the fifth cause of cancer death worldwide.
Although survival has improved with second-generation androgen signaling and Parp …
Although survival has improved with second-generation androgen signaling and Parp …
The role of obesity and bariatric surgery-induced weight loss in breast cancer
Obesity is a complex metabolic condition considered a worldwide public health crisis, and a
deeper mechanistic understanding of obesity-associated diseases is urgently needed …
deeper mechanistic understanding of obesity-associated diseases is urgently needed …
Microbiome, bile acids, and obesity: How microbially modified metabolites shape anti‐tumor immunity
Bile acids (BAs) are known facilitators of nutrient absorption but recent paradigm shifts now
recognize BAs as signaling molecules regulating both innate and adaptive immunity. Bile …
recognize BAs as signaling molecules regulating both innate and adaptive immunity. Bile …
Posttranscriptional control of PD-L1 expression by 17β-estradiol via PI3K/Akt signaling pathway in ERα-positive cancer cell lines
Objective Estrogen is a well-known oncogenic driver in endometrial (ECs) and breast
cancers (BCs). Programmed cell death protein 1 (PD-1) and its ligands PD-1 Ligand 1 (PD …
cancers (BCs). Programmed cell death protein 1 (PD-1) and its ligands PD-1 Ligand 1 (PD …
What do we have to know about PD-L1 expression in prostate cancer? A systematic literature review. Part 1: Focus on immunohistochemical results with discussion of …
A Palicelli, M Bonacini, S Croci, C Magi-Galluzzi… - Cells, 2021 - mdpi.com
Immunotherapy targeting the PD-1–PD-L1 axis yielded good results in treating different
immunologically ''hot''tumors. A phase II study revealed good therapeutic activity of …
immunologically ''hot''tumors. A phase II study revealed good therapeutic activity of …