[HTML][HTML] Recent Technologies towards Diagnostic and Therapeutic Applications of Circulating Nucleic Acids in Colorectal Cancers

J Chung, S Xiao, Y Gao, YH Soung - International Journal of Molecular …, 2024 - mdpi.com
Liquid biopsy has emerged as a promising noninvasive approach for colorectal cancer
(CRC) management. This review focuses on technologies detecting circulating nucleic …

How MicroRNAs Command the Battle against Cancer

HH Wu, S Leng, C Sergi, R Leng - International Journal of Molecular …, 2024 - mdpi.com
MicroRNAs (miRNAs) are small RNA molecules that regulate more than 30% of genes in
humans. Recent studies have revealed that miRNAs play a crucial role in tumorigenesis …

5‐Fluorouracil treatment represses pseudouridine‐containing miRNA export into extracellular vesicles

S Qu, HM Nelson, X Liu, Y Wang… - Journal of …, 2024 - Wiley Online Library
Fluorouracil (5‐FU) has been used for chemotherapy for colorectal and other cancers for
over 50 years. The prevailing view of its mechanism of action is inhibition of thymidine …

Unraveling the Multifaceted Role of the miR-17-92 Cluster in Colorectal Cancer: From Mechanisms to Biomarker Potential

HH Al-Nakhle - Current Issues in Molecular Biology, 2024 - mdpi.com
Colorectal cancer (CRC) is a complex disease driven by intricate mechanisms, making it
challenging to understand and manage. The miR-17-92 cluster has gained significant …