Regeneration is one of the great mysteries of biology. Planarians are flatworms capable of
dramatic feats of regeneration, which have been studied for over 2 centuries. Recent …

Planarians have a long history in the fields of developmental and regenerative biology.
These animals have also sparked interest in neuroscience due to their neuroanatomy …

Animals are grouped into~ 35 'phyla'based upon the notion of distinct body plans,,,.
Morphological and molecular analyses have revealed that a stage in the middle of …

Planarian flatworms regenerate every organ after amputation. Adult pluripotent stem cells
drive this ability, but how injury activates and directs stem cells into the appropriate lineages …

Abstract Background The planarian Schmidtea mediterranea is a master regenerator with a
large adult stem cell compartment. The lack of transgenic labeling techniques in this animal …

Planarian neoblasts are pluripotent, adult somatic stem cells and lineage-primed
progenitors that are required for the production and maintenance of all differentiated cell …

Background Freshwater planarians are well known for their regenerative abilities. Less well
known is how planarians maintain spatial patterning in long-lived adult animals or how they …

Advances in stem cell biology have led to the derivation of diverse cell types, yet challenges
remain in creating complex tissues and functional organs. Unlike humans, some animals …

The Wingless/Integrated (Wnt) signaling pathway controls multiple events during
development and homeostasis. It comprises multiple branches, mainly classified according …

Flatworm embryology has attracted attention since the early beginnings of comparative
evolutionary biology. Considered for a long time the most basal bilaterians, the …