Recombinant Pseudorabies Virus Usage in Vaccine Development against Swine Infectious Disease

M Zhou, M Abid, S Cao, S Zhu - Viruses, 2023 - mdpi.com
Pseudorabies virus (PRV) is the pathogen of pseudorabies (PR), which belongs to the alpha
herpesvirus subfamily with a double stranded DNA genome encoding approximately 70 …

Generation and immunogenicity of a recombinant pseudorabies virus co-expressing classical swine fever virus E2 protein and porcine circovirus type 2 capsid protein …

M Abid, T Teklue, Y Li, H Wu, T Wang, HJ Qiu, Y Sun - Pathogens, 2019 - mdpi.com
Pseudorabies (PR), classical swine fever (CSF), and porcine circovirus type 2 (PCV2)-
associated disease (PCVAD) are economically important infectious diseases of pigs. Co …

The mutations on the envelope glycoprotein D contribute to the enhanced neurotropism of the pseudorabies virus variant

H Wu, H Qi, B Wang, M Li, L Qu, S Li, Y Luo… - Journal of Biological …, 2023 - ASBMB
The pseudorabies virus (PRV) TJ strain, a variant of PRV, induces more severe neurological
symptoms and higher mortality in piglets and mice than the PRV SC strain isolated in 1980 …

A rapid and versatile reverse genetic approach and visualization animal models for emerging zoonotic pseudorabies virus

Y Zhang, X Li, J Zhang, Y Duan, P Chen, L Shi… - Antiviral Research, 2024 - Elsevier
Pseudorabies virus (PRV), a member of the Alphaherpesvirinae subfamily and a causative
pathogen of Aujeszky's disease, has a broad host range including domestic and wild …

Establishment of a fosmid library for pseudorabies virus SC strain and application in viral neuronal tracing

H Qi, H Wu, M Abid, HJ Qiu, Y Sun - Frontiers in Microbiology, 2020 - frontiersin.org
Pseudorabies virus (PRV) is a member of Alphaherpesvirinae subfamily, its neurotropism
and latency infection attract the attention of many scientists. PRV tagged with a fluorescent …

A Recombinant System and Reporter Viruses for Papiine Alphaherpesvirus 2

A Rahman Siregar, S Gärtner, J Götting, P Stegen… - Viruses, 2022 - mdpi.com
Primate simplex viruses, including Herpes simplex viruses 1 and 2, form a group of closely
related herpesviruses, which establish latent infections in neurons of their respective host …

Dual-fluorescence labeling of pseudorabies virus for live-cell tracking virus entry and replication

H Wu, M Li, L Pan, G Xiang, LF Li, T Wang, R Luo, Y Li… - 2024 - researchsquare.com
Pseudorabies virus (PRV) is a neurotropic herpesvirus. It is not easy to tracking the whole
replication progess of PRV, especially the nascent viral genome in the host cells. In this …

A Fosmid-Based System for the Generation of Recombinant Cercopithecine Alphaherpesvirus 2 Encoding Reporter Genes

E Chukhno, S Gärtner, A Rahman Siregar, A Mehr… - Viruses, 2019 - mdpi.com
The transmission of Macacine alphaherpesvirus 1 (McHV-1) from macaques, the natural
host, to humans causes encephalitis. In contrast, human infection with Cercopithecine …

Establishment of an In Vitro Model of Pseudorabies Virus Latency and Reactivation and Identification of Key Viral Latency-Associated Genes

L Pan, M Li, X Zhang, Y Xia, AM Mian, H Wu, Y Sun… - Viruses, 2023 - mdpi.com
Alphaherpesviruses infect humans and most animals. They can cause severe morbidity and
mortality. The pseudorabies virus (PRV) is a neurotropic alphaherpesvirus that can infect …