Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using machine learning
Early use of effective antimicrobial treatments is critical for the outcome of infections and the
prevention of treatment resistance. Antimicrobial resistance testing enables the selection of …
prevention of treatment resistance. Antimicrobial resistance testing enables the selection of …
Sample-to-result molecular diagnostic platforms and their suitability for infectious disease testing in low-and middle-income countries
A Hauner, C Onwuchekwa, KK Ariën - Expert review of molecular …, 2024 - Taylor & Francis
Introduction Diagnostics are an essential, undervalued part of the health-care system. For
many diseases, molecular diagnostics are the gold standard, but are not easy to implement …
many diseases, molecular diagnostics are the gold standard, but are not easy to implement …
Comparison of the NG-test carba 5, colloidal gold immunoassay (CGI) test, and Xpert carba-R for the rapid detection of carbapenemases in carbapenemase …
D Gu, Z Yan, C Cai, J Li, Y Zhang, Y Wu, J Yang… - Antibiotics, 2023 - mdpi.com
Carbapenem-resistant Enterobacterales (CRE) are increasingly recognized as an urgent
public health concern. The rapid and accurate identification of carbapenemases could …
public health concern. The rapid and accurate identification of carbapenemases could …
Detection of Carbapenem-resistance in CRE by Comparative Assessment of RAPIDEC® CARBA NP and Xpert™Carba-R Assay
RA Eltahlawi, A Jiman-Fatani, NM Gad… - Infection and Drug …, 2023 - Taylor & Francis
Introduction Carbapenem-resistant Enterobacteriaceae (CRE) infections resist nearly most
available antimicrobials, resulting in poor clinical outcomes. Saudi Arabia has a relatively …
available antimicrobials, resulting in poor clinical outcomes. Saudi Arabia has a relatively …
The molecular detection of carbapenem markers with a two-levels amplification screening protocol: epidemiological and resistome insights
M Calvo, G Migliorisi, G Maugeri, D Bongiorno… - Frontiers in …, 2024 - frontiersin.org
Objectives Carbapenem-resistance is a challenging healthcare concern and require specific
stewardship programs. Monitoring workflows include the identification from surveillance …
stewardship programs. Monitoring workflows include the identification from surveillance …
Evaluation of the Novodiag CarbaR+, a novel integrated sample to result platform for the multiplex qualitative detection of carbapenem and colistin resistance markers
D Girlich, P Bogaerts, W Bouchahrouf… - Microbial Drug …, 2021 - liebertpub.com
Objectives: This study evaluated the performance of the Novodiag® CarbaR+ an automated
qualitative nucleic acid-based diagnostic assay detecting the bla VIM, bla NDM, bla IMP, bla …
qualitative nucleic acid-based diagnostic assay detecting the bla VIM, bla NDM, bla IMP, bla …
Performance of two methods of carbapenem-resistant Enterobacterales surveillance on a kidney transplant ward: selective culture of and real-time PCR directly from …
MP Freire, D de Oliveira Garcia, SG Lima, CRD Pea… - Infection, 2022 - Springer
Background Infection with carbapenem-resistant Enterobacterales (CRE) is associated with
a high mortality rate in kidney transplant recipients, and colonization with CRE is one of the …
a high mortality rate in kidney transplant recipients, and colonization with CRE is one of the …
Evaluation of the Xpert Carba-R assay for quantifying carbapenemase-producing bacterial load in stool samples
JY Chua, ZQ Lim, SQD Loy, V Koh, NM Thevasagayam… - Plos one, 2024 - journals.plos.org
Background The spread of Carbapenemase-producing Organisms (CPO) remains a major
threat globally. Within clinical settings, the existing method of determining gene load …
threat globally. Within clinical settings, the existing method of determining gene load …
[HTML][HTML] Accuracy of Xpert Carba-R assay for the diagnosis of carbapenemase-producing organisms from rectal swabs and clinical isolates: a meta-analysis of …
Y Bai, Y Hao, C Shao, Y Wang, Y Jin - The Journal of Molecular …, 2021 - Elsevier
The Cepheid Xpert Carba-R assay has demonstrated a promising value for the detection of
carbapenemase-producing organisms, but its diagnostic performance remains unclear …
carbapenemase-producing organisms, but its diagnostic performance remains unclear …
[HTML][HTML] Active Surveillance of Patients Colonized with CRE: A Single-Center Study Based on a Combined Molecular/Culture Protocol
BS Orena, MF Liporace, A Teri, D Girelli, F Salari… - Antibiotics, 2024 - mdpi.com
Background/Objectives: Carbapenem-resistant Enterobacteriaceae (CRE) are types of
bacteria that need urgent attention globally. Active surveillance programs at hospitals are …
bacteria that need urgent attention globally. Active surveillance programs at hospitals are …