Gastric cancer: basic aspects

C Resende, A Thiel, JC Machado, A Ristimäki - Helicobacter, 2011 - Wiley Online Library
Gastric cancer (GC) is a world health burden, ranging as the second cause of cancer death
worldwide. Etiologically, GC arises not only from the combined effects of environmental …

Critical review of Epstein–Barr virus microRNAs relation with EBV‐associated gastric cancer

A Zebardast, SS Tehrani, T Latifi… - Journal of cellular …, 2021 - Wiley Online Library
Abstract Epstein–Barr virus (EBV)‐associated gastric cancer (EBVaGC) is regarded as the
most prevalent malignant tumor triggered by EBV infection. In recent years, increasing …

EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN

LM Cai, XM Lyu, WR Luo, XF Cui, YF Ye, CC Yuan… - Oncogene, 2015 - nature.com
The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and
metastasis. Although multiple cellular miRNAs have been identified to regulate the EMT and …

Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of …

BJ Choi, SA Park, SY Lee, YN Cha, YJ Surh - Scientific reports, 2017 - nature.com
During the metastatic phase, cancer cells require the dissolution of cadherin-mediated cell-
cell adhesion and a dramatic re-organization of the cytoskeleton through epithelial …

ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition

D Nagarajan, T Melo, Z Deng, C Almeida… - Free Radical Biology and …, 2012 - Elsevier
Radiotherapy is one of the major treatment regimes for thoracic malignancies, but can lead
to severe lung complications including pneumonitis and fibrosis. Recent studies suggest that …

PI3K/Akt-dependent phosphorylation of GSK3β and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration

J Liu, Y Zhang, R Xu, J Du, Z Hu, L Yang, Y Chen… - Cellular signalling, 2013 - Elsevier
Wnt5a, a non-transforming Wnt family member, plays complicated roles in oncogenesis and
cancer metastasis. However, Wnt5a signaling in gastric cancer progression remains poorly …

[HTML][HTML] Glycogen synthase kinase-3 beta regulates Snail and β-catenin expression during Fas-induced epithelial–mesenchymal transition in gastrointestinal cancer

H Zheng, W Li, Y Wang, Z Liu, Y Cai, T Xie… - European journal of …, 2013 - Elsevier
Fas signalling has been shown to induce the epithelial–mesenchymal transition (EMT) to
promote gastrointestinal (GI) cancer metastasis, but its mechanism of action is still unknown …

[HTML][HTML] Akt2 mediates TGF-β1-induced epithelial to mesenchymal transition by deactivating GSK3β/snail signaling pathway in renal tubular epithelial cells

A Lan, Y Qi, J Du - Cellular Physiology and Biochemistry, 2014 - karger.com
Background: The epithelial-mesenchymal transition (EMT) induced by growth factors or
cytokines, particularly transforming growth factor-β (TGF-β1), plays an important role in …

Genetic Alterations in Gastric Cancer Associated with Helicobacter pylori Infection

CI Rivas-Ortiz, Y Lopez-Vidal… - Frontiers in …, 2017 - frontiersin.org
Gastric cancer is a world health problem and depicts the fourth leading mortality cause from
malignancy in Mexico. Causation of gastric cancer is not only due to the combined effects of …

The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

WZ Qiu, HB Zhang, WX Xia, LR Ke, J Yang… - Journal of Experimental …, 2018 - Springer
Background Distant metastasis is the major cause of treatment failure in patients with
nasopharyngeal carcinoma (NPC). Although several biomarkers correlate with metastasis …