Cannabis‐based medicines for chronic neuropathic pain in adults

M Mücke, T Phillips, L Radbruch… - … of systematic reviews, 2018 - cochranelibrary.com
Background This review is one of a series on drugs used to treat chronic neuropathic pain.
Estimates of the population prevalence of chronic pain with neuropathic components range …

Cannabinoid delivery systems for pain and inflammation treatment

N Bruni, C Della Pepa, S Oliaro-Bosso, E Pessione… - Molecules, 2018 - mdpi.com
There is a growing body of evidence to suggest that cannabinoids are beneficial for a range
of clinical conditions, including pain, inflammation, epilepsy, sleep disorders, the symptoms …

[PDF][PDF] Current understanding of phantom pain and its treatment

CJ Culp, S Abdi - Pain physician, 2022 - painphysicianjournal.com
Background: Phantom limb pain (PLP), defined as a painful sensation in a portion of the
body that has been amputated, occurs in upwards of 80% of limb amputees and can …

Animal models of chronic pain: advances and challenges for clinical translation

NE Burma, H Leduc‐Pessah, CY Fan… - Journal of …, 2017 - Wiley Online Library
Chronic pain is a global problem that has reached epidemic proportions. An estimated 20%
of adults suffer from pain, and another 10% are diagnosed with chronic pain each year …

European consensus‐based (S2k) Guideline on the Management of Herpes Zoster–guided by the European Dermatology Forum (EDF) in cooperation with the …

RN Werner, AF Nikkels, B Marinović… - Journal of the …, 2017 - Wiley Online Library
Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the
quality of life of affected patients. Different therapeutic approaches to treat acute HZ are …

Spinal microglia are required for long-term maintenance of neuropathic pain

S Echeverry, XQ Shi, MU Yang, H Huang, YC Wu… - Pain, 2017 - journals.lww.com
While spinal microglia play a role in early stages of neuropathic pain etiology, whether they
are useful targets to reverse chronic pain at late stages remains unknown. Here, we show …

[PDF][PDF] Chronic pain in the elderly: the case for new therapeutic strategies

A Paladini, M Fusco, S Coaccioli… - Pain …, 2015 - painphysicianjournal.com
Background: Elderly patients in general exhibit a higher incidence of chronic and
neuropathic pain conditions. This group poses a particular clinical challenge due to age …

Modular characteristics and mechanism of action of herbs for endometriosis treatment in Chinese medicine: a data mining and network pharmacology–based …

W Zheng, J Wu, J Gu, H Weng, J Wang… - Frontiers in …, 2020 - frontiersin.org
Endometriosis is a common benign disease in women of reproductive age. It has been
defined as a disorder characterized by inflammation, compromised immunity, hormone …

JWH-182: a safe and effective synthetic cannabinoid for chemotherapy-induced neuropathic pain in preclinical models

LE Filipiuc, I Creangă-Murariu, BI Tamba… - Scientific Reports, 2024 - nature.com
Chemotherapy-induced neuropathic pain (CINP), a condition with unmet treatment needs,
affects over half of cancer patients treated with chemotherapeutics. Researchers have …

Dynamics of spinal microglia repopulation following an acute depletion

Y Yao, S Echeverry, XQ Shi, M Yang, QZ Yang… - Scientific reports, 2016 - nature.com
Our understanding on the function of microglia has been revolutionized in the recent 20
years. However, the process of maintaining microglia homeostasis has not been fully …