Antibiotic resistance: turning evolutionary principles into clinical reality

DI Andersson, NQ Balaban, F Baquero… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

Current and emerging topical antibacterials and antiseptics: agents, action, and resistance patterns

DA Williamson, GP Carter… - Clinical microbiology …, 2017 - Am Soc Microbiol
Bacterial skin infections represent some of the most common infectious diseases globally.
Prevention and treatment of skin infections can involve application of a topical antimicrobial …

Tackling threats and future problems of multidrug-resistant bacteria

E Medina, DH Pieper - How to overcome the antibiotic crisis: facts …, 2016 - Springer
With the advent of the antibiotic era, the overuse and inappropriate consumption and
application of antibiotics have driven the rapid emergence of multidrug-resistant pathogens …

Origin, evolution, and global transmission of community-acquired Staphylococcus aureus ST8

L Strauß, M Stegger, PE Akpaka… - Proceedings of the …, 2017 - National Acad Sciences
USA300 is a pandemic clonal lineage of hypervirulent, community-acquired, methicillin-
resistant Staphylococcus aureus (CA-MRSA) with specific molecular characteristics. Despite …

[HTML][HTML] Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs

HM Kemung, LTH Tan, TM Khan, KG Chan… - Frontiers in …, 2018 - frontiersin.org
Methicillin-resistant Staphylococcus aureus (MRSA) pose a significant health threat as they
tend to cause severe infections in vulnerable populations and are difficult to treat due to a …

Genomic insights into the emergence and spread of international clones of healthcare-, community-and livestock-associated meticillin-resistant Staphylococcus …

AM Bal, GW Coombs, MTG Holden, JA Lindsay… - Journal of Global …, 2016 - Elsevier
The evolution of meticillin-resistant Staphylococcus aureus (MRSA) from meticillin-
susceptible S. aureus has been a result of the accumulation of genetic elements under …

[HTML][HTML] Molecular epidemiology of Methicillin-resistant Staphylococcus aureus in Africa: a systematic review

SM Abdulgader, AO Shittu, MP Nicol… - Frontiers in …, 2015 - frontiersin.org
Methicillin-resistant Staphylococcus aureus (MRSA) infections are a serious global problem,
with considerable impact on patients and substantial health care costs. This systematic …

[HTML][HTML] Staphylococcus aureus in Animals and Food: Methicillin Resistance, Prevalence and Population Structure. A Review in the African Continent

C Lozano, H Gharsa, K Ben Slama, M Zarazaga… - Microorganisms, 2016 - mdpi.com
The interest about Staphylococcus aureus (S. aureus) and methicillin resistant S. aureus
(MRSA) in livestock, and domestic and wild animals has significantly increased. The spread …

Longitudinal genomic surveillance of MRSA in the UK reveals transmission patterns in hospitals and the community

F Coll, EM Harrison, MS Toleman, S Reuter… - Science translational …, 2017 - science.org
Genome sequencing has provided snapshots of the transmission of methicillin-resistant
Staphylococcus aureus (MRSA) during suspected outbreaks in isolated hospital wards …

ESKAPE pathogens: antimicrobial resistance, epidemiology, clinical impact and therapeutics

WR Miller, CA Arias - Nature Reviews Microbiology, 2024 - nature.com
The rise of antibiotic resistance and a dwindling antimicrobial pipeline have been
recognized as emerging threats to public health. The ESKAPE pathogens—Enterococcus …