The four-dimensional nucleome (4DN) consortium studies the architecture of the genome
and the nucleus in space and time. We summarize progress by the consortium and highlight …

Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

Public archiving in structural biology is well established with the Protein Data Bank (PDB;
wwPDB. org) catering for atomic models and the Electron Microscopy Data Bank (EMDB; …

Abstract WashU Epigenome Browser (https://epigenomegateway. wustl. edu/browser/) is a
web-based genomic data exploration tool that provides visualization, integration, and …

Volume electron microscopy (vEM) is a group of techniques that reveal the 3D ultrastructure
of cells and tissues through continuous depths of at least 1 micrometer. A burgeoning …

A growing community is constructing a next-generation file format (NGFF) for bioimaging to
overcome problems of scalability and heterogeneity. Organized by the Open Microscopy …

Abstract The European Bioinformatics Institute (EMBL-EBI) maintains a comprehensive
range of freely available and up-to-date molecular data resources, which includes over 40 …

Despite the huge impact of data resources in genomics and structural biology, until now
there has been no central archive for biological data for all imaging modalities. The …

The imminent release of tissue atlases combining multichannel microscopy with single-cell
sequencing and other omics data from normal and diseased specimens creates an urgent …

The community-driven initiative Quality Assessment and Reproducibility for Instruments &
Images in Light Microscopy (QUAREP-LiMi) wants to improve reproducibility for light …